Synthesis of fully substituted pyrazolo[3,4-b]pyridine-5-carboxamide derivatives via a one-pot four-component reaction

被引：52
|
作者：
Shaabani, Ahmad [1 ]
Seyyedhamzeh, Mozhdeh [1 ]
Maleki, Ali [1 ]
Behnam, Maryam [1 ]
Rezazadeh, Fahimeh [1 ]
机构：
[1] Shahid Beheshti Univ, Dept Chem, Tehran, Iran
来源：
TETRAHEDRON LETTERS | 2009年 / 50卷 / 24期
关键词：
Pyrazolo[3,4-b]pyridine-5-carboxamide; Multicomponent reaction; One-pot; 1,3-Diphenyl-1H-pyrazol-5-amine; Diketene; MICROWAVE IRRADIATION; INHIBITORS; ALPHA;
D O I：
10.1016/j.tetlet.2009.03.200
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A one-pot four-component reaction of an aliphatic or aromatic amine, diketene, an aromatic aldehyde and 1,3-diphenyl-1H-pyrazol-5-amine in the presence of p-toluenesulfonic acid as a catalyst has been developed. In this reaction, a new class of fully substituted pyrazolo[3,4-b]pyridine-5-carboxamide derivatives is produced under mild reaction conditions and in good yields at ambient temperature. (C) 2009 Published by Elsevier Ltd.
引用
收藏
页码：2911 / 2913
页数：3
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