Dermatological complications and safety of anti-TNF treatments

被引:71
|
作者
Kerbleski, Joseph F. [1 ]
Gottlieb, Alice B. [1 ]
机构
[1] Tufts Med Ctr, Dept Dermatol, Boston, MA 02111 USA
关键词
TUMOR-NECROSIS-FACTOR; RHEUMATOID-ARTHRITIS; INFUSION REACTIONS; FACTOR-ALPHA; COMBINATION THERAPY; CROHNS-DISEASE; RISK-FACTORS; INFLIXIMAB; INFECTIONS; MANAGEMENT;
D O I
10.1136/gut.2008.163683
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
It has been reported that tumour necrosis factor (TNF) inhibitors have adverse side-effects including infections, malignancies, demyelinating disease, and induction of autoimmune conditions. Dermatological complications of anti-TNF therapy include injection site reactions, cutaneous infections, allergic rashes, psoriasis, non-melanoma skin cancer (NMSC), and rare reports of lupus-like syndrome, erythema multiforme (EM), Steven's Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN).
引用
收藏
页码:1033 / 1039
页数:7
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