Vagus somatosensory evoked potentials are delayed in Alzheimer's disease, but not in major depression

被引：16

作者：

Polak, Thomas ^{[1
]}

Dresler, Thomas ^{[2
]}

Zeller, Julia B. M. ^{[1
]}

Warrings, Bodo ^{[1
]}

Scheuerpflug, Peter ^{[3
]}

Fallgatter, Andreas J. ^{[2
]}

Deckert, Juergen ^{[1
]}

Metzger, Florian G. ^{[2
]}

机构：

[1] Univ Clin Wuerzburg, Dept Psychiat Psychosomat & Psychotherapy, D-97080 Wurzburg, Germany

[2] Univ Clin Tuebingen, Dept Psychiat & Psychotherapy, D-72076 Tubingen, Germany

[3] Univ Clin Wuerzburg, Dept Child & Adolescent Psychiat, D-97080 Wurzburg, Germany

来源：

EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE | 2014年 / 264卷 / 03期

关键词：

Neurodegenerative diseases; Affective disorders; Evoked potentials technology; Differential diagnosis; Early diagnosis; FAR-FIELD POTENTIALS; DORSAL RAPHE NUCLEUS; BRAIN-STEM; NERVE; DIAGNOSIS; DISORDER;

D O I：

10.1007/s00406-013-0415-2

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

In Alzheimer's disease (AD), the degeneration of brainstem nuclei is different from major depression (MD). Thus, vagus somatosensory evoked potentials (VSEP) proposed for the functional assessment of brainstem nuclei should show prolonged latencies in AD but not in MD. In 55 AD patients, 57 MD patients and two age-matched control groups evoked potentials were recorded upon stimulation of the auricular branch of the vagus nerve. In the AD, not in the MD group, latencies were significantly longer as compared to controls. Thus, the method of VSEP could contribute to the important differential diagnosis of AD and MD in elderly patients.

引用

页码：263 / 267

页数：5

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