FREQUENCY OF VACCINATED CHILDREN AMONG MEASLES CASES

Aim: To estimate the frequency of vaccinated children among measles cases Methods: One hundred and thirty 130 diagnosed cases measles (presence of typical maculopapular rash or pathognomonic koplik's spots, fever and any of these coughs, coryza or conjunctivitis) of either gender with age range of 1-12 years were selected from Pediatric Department of Federal Government Polyclinic Hospital, Islamabad. Detailed history and clinical examination for measles considering their medical record regarding vaccination status was done. The frequency of vaccinated children among measles cases was noted. Results: In this study, out of 150 cases in Rifaximin Group, 30.67%(n=23) and 36%(n=27) were between 20-50 years of age while 69.33%(n=52) in Rifaximin and 64%(n=48) in Placebo Group were between 51-80 years of age, mean+sd was calculated as 54.42 +/- 9.21 years and 56.14 +/- 10.81 years respectively, 49.33%(n=37) in Rifaximin and 45.33%(n=34) in Placebo Group were males whereas 50.67%(n=38) in Rifaximin and 54.67%(n=41) in Placebo group were males. On comparison of both groups, we found recurrence rate as 28% in Rifaxomin and 53.33% in Placebo group, p value was 0.002 showing a significant lower rate in Rifaximin group. Conclusion: The use of rifaximin shows significantly lower rate of recurrence of hepatic encephalopathy when compared to placebo