Mammary development meets cancer genomics

被引：144
|
作者：
Prat, Aleix [1 ,2 ]
Perou, Charles M. [1 ,2 ]
机构：
[1] Univ N Carolina, Lineberger Comprehens Canc Ctr, Dept Genet, Chapel Hill, NC 27599 USA
[2] Univ N Carolina, Lineberger Comprehens Canc Ctr, Dept Pathol & Lab Med, Chapel Hill, NC 27599 USA
来源：
NATURE MEDICINE | 2009年 / 15卷 / 08期
关键词：
INVASIVE BREAST-CARCINOMA; BASAL-LIKE SUBTYPE; MOLECULAR PORTRAITS; STEM-CELLS; TUMORS;
D O I：
10.1038/nm0809-842
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Mammary epithelial cell development is thought to progress from undifferentiated stem cells into at least two differentiated cell types. A new study has now characterized some of these distinct developmental stages and links them to tumor subtypes previously defined by gene expression profiling (pages 907-913).
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页码：842 / 844
页数：4
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