Pleckstrin 2, a paralog of pleckstrin, binds products of PI3K.

被引:0
|
作者
Bauman, EM [1 ]
Hu, MH [1 ]
Kine, P [1 ]
Sankaran, VG [1 ]
Yeilding, N [1 ]
Lemmon, MA [1 ]
Abrams, CS [1 ]
机构
[1] Univ Penn, Philadelphia, PA 19104 USA
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
960
引用
收藏
页码:218A / 218A
页数:1
相关论文
共 50 条
  • [1] Pleckstrin 2, a widely expressed paralog of pleckstrin involved in actin rearrangement
    Hu, MH
    Bauman, EM
    Roll, RL
    Yeilding, N
    Abrams, CS
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (31) : 21515 - 21518
  • [2] PI3K regulates pleckstrin-2 in T-cell cytoskeletal reorganization
    Bach, Tami L.
    Kerr, Wesley T.
    Wang, Yanfeng
    Bauman, Eve Marie
    Kine, Purnima
    Whiteman, Eileen L.
    Morgan, Renell S.
    Williamson, Edward K.
    Ostap, E. Michael
    Burkhardt, Janis K.
    Koretzky, Gary A.
    Birnbaum, Morris J.
    Abrams, Charles S.
    BLOOD, 2007, 109 (03) : 1147 - 1155
  • [3] Null mutation of pleckstrin2, a PI3K effector, impairs platelet secretion.
    Wang, YF
    Lian, LR
    Abrams, CS
    BLOOD, 2004, 104 (11) : 959A - 959A
  • [4] Targeting pleckstrin-2 for the JAK2-STAT and PI3K-Akt pathways in cancer therapy
    Han, Xu
    Mei, Yang
    Schiltz, Gary E.
    Mishra, Rama K.
    Jain, Atul D.
    Ji, Peng
    CANCER RESEARCH, 2019, 79 (13)
  • [5] PI3K regulates pleckstrin-2 in T-cell cytoskeletal re-organization
    Bach, TL
    Kerr, WT
    Abrams, CS
    BLOOD, 2005, 106 (11) : 924A - 924A
  • [6] Identification of Toxoplasma TgPH1, a pleckstrin homology domain-containing protein that binds to the phosphoinositide PI(3,5)P2
    Daher, Wassim
    Morlon-Guyot, Juliette
    Alayi, Tchilabalo Dilezitoko
    Tomavo, Stan
    Wengelnik, Kai
    Lebrun, Maryse
    MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 2016, 207 (01) : 39 - 44
  • [8] PI3K/AKT pathway activation in acute myeloid leukaemias is not associated with AKT1 pleckstrin homology domain mutation
    Tibes, Raoul
    Kornblau, Steven M.
    Qiu, Yihua
    Mousses, Spyro M.
    Robbins, Christiane
    Moses, Tracy
    Carpten, John D.
    BRITISH JOURNAL OF HAEMATOLOGY, 2008, 140 (03) : 344 - 347
  • [9] Irreversible platelet aggregation and prolonged pleckstrin phosphorylation are mediated by the lipid products of phosphatidylinositol 3-kinase.
    Kovacsovics, TJ
    Hartwig, JH
    Cantley, LC
    Toker, A
    BLOOD, 1995, 86 (10) : 2439 - 2439
  • [10] Pleckstrin-2 selectively interacts with phosphatidylinositol 3-kinase lipid products and regulates actin organization and cell spreading
    Hamaguchi, Norihisa
    Ihara, Sayoko
    Ohdaira, Tsutomu
    Nagano, Hiromichi
    Iwamatsu, Akihiro
    Tachikawa, Hiroyuki
    Fukui, Yasuhisa
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2007, 361 (02) : 270 - 275