Mitochondrial NADH dehydrogenase activity and ability to tolerate acetaldehyde determine faster ethanol production in Saccharomyces cerevisiae

被引:0
|
作者
Shankar, CS [1 ]
Ahamad, PYA [1 ]
Ramakrishnan, MS [1 ]
UmeshKumar, S [1 ]
机构
[1] CENT FOOD TECHNOL RES INST, DEPT FOOD MICROBIOL, MYSORE 570013, KARNATAKA, INDIA
来源
BIOCHEMISTRY AND MOLECULAR BIOLOGY INTERNATIONAL | 1996年 / 40卷 / 01期
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中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
In rapidly fermenting yeast, the rotenone insensitive mitochondrial NADH dehydrogenase was not completely repressed by high glucose. This activity appeared to enhance the glycolytic rate due to which acetaldehyde accumulated intracellularly. To overcome the toxicity of acetaldehyde, the strain produced stress proteins. During late stationary phase of growth, the accumulated acetaldehyde was converted to ethanol resulting in faster ethanol production.
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页码:145 / 150
页数:6
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