Orexin (hypocretin) gene transfer improves narcoleptic symptoms in orexin null mice

被引：0
|
作者：
Liu, M. [1 ]
Thankachan, S. [1 ]
Kaur, S. [1 ]
Sakurai, T. [3 ]
Yanagisawa, M. [4 ]
Neve, R. L. [2 ]
Shiromani, P. J. [1 ]
机构：
[1] Harvard Univ, Sch Med, W Roxbury, MA USA
[2] Harvard Univ, McLean Hosp, Sch Med, Belmont, MA 02178 USA
[3] Kanazawa Univ, Kanazawa, Ishikawa, Japan
[4] Univ Texas SW Med Ctr Dallas, Dallas, TX 75390 USA
来源：
JOURNAL OF SLEEP RESEARCH | 2008年 / 17卷
关键词：
D O I：
暂无
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
引用
收藏
页码：26 / 27
页数：2
相关论文
共 50 条
  • [1] Orexin (hypocretin) gene transfer improves narcoleptic symptoms in orexin null mice
    Liu, M.
    Thankachan, S.
    Kaur, S.
    Begum, S.
    Blanco-Centurion, C.
    Sakurai, T.
    Yanagisawa, M.
    Neve, R.
    Shiromani, P.
    SLEEP, 2008, 31 : A212 - A212
  • [2] Orexin (hypocretin) gene transfer diminishes narcoleptic sleep behavior in mice
    Liu, Meng
    Thankachan, Stephen
    Kaur, Satvinder
    Begum, Suraiya
    Blanco-Centurion, Carlos
    Sakurai, Takeshi
    Yanagisawa, Masashi
    Neve, Rachael
    Shiromani, Priyattam J.
    EUROPEAN JOURNAL OF NEUROSCIENCE, 2008, 28 (07) : 1382 - 1393
  • [3] Site-specific effects of orexin gene transfer in narcoleptic mice
    Shiromani, P.
    Liu, M.
    Blanco-Centurion, C.
    Konadhode, R.
    Pelluru, D.
    JOURNAL OF SLEEP RESEARCH, 2012, 21 : 40 - 41
  • [4] OREXIN GENE TRANSFER INTO THE ZONA INCERTA NEURONS BLOCKS CATAPLEXY AND IMPROVES WAKE MAINTENANCE IN NARCOLEPTIC OREXIN-ATAXIN-3 TRANSGENIC MICE
    Blanco-Centurion, C.
    Liu, M.
    Konadhode, R.
    Pelluru, D.
    van den Pol, A.
    Shiromani, P. J.
    SLEEP, 2012, 35 : A9 - A9
  • [5] Hypocretin receptor expressions in hypocretin neuron ablated (Orexin/Ataxin-3 transgenic) narcoleptic mice
    Mishima, K
    Fujiki, N
    Yoshino, F
    Yoshida, Y
    Sakurai, T
    Nishino, S
    SLEEP, 2005, 28 : A215 - A215
  • [6] Attenuated amphetamine induced locomotor sensitization in hypocretin/Orexin-deficient narcoleptic mice
    Fujiki, N
    Yoshino, F
    Yoshida, Y
    Sakurai, T
    Yanagisawa, M
    Nishino, S
    SLEEP, 2005, 28 : A219 - A219
  • [7] Distribution of hypocretin (Orexin) immunoreactivity in the hypothalamus of normal and narcoleptic horse
    Thannickal, TC
    Mayhew, J
    Blouin, A
    Nienhuis, R
    Williams, AJ
    Ebrahim, IO
    Siegel, JM
    SLEEP, 2004, 27 : 240 - 241
  • [8] Orexin Gene Transfer into Zona Incerta Neurons Suppresses Muscle Paralysis in Narcoleptic Mice
    Liu, Meng
    Blanco-Centurion, Carlos
    Konadhode, RodaRani
    Begum, Suraiya
    Pelluru, Dheeraj
    Gerashchenko, Dmitry
    Sakurai, Takeshi
    Yanagisawa, Masashi
    van den Pol, Anthony N.
    Shiromani, Priyattam J.
    JOURNAL OF NEUROSCIENCE, 2011, 31 (16): : 6028 - 6040
  • [9] The effects of hypocretin-1 (Orexin A) in hypocretin receptor 2 gene mutated and hypocretin ligand-deficient narcoleptic dogs
    Nishino, S
    Fujiki, N
    Yoshida, Y
    Mignot, E
    SLEEP, 2003, 26 : A287 - A287
  • [10] Normal plasma levels of orexin A (hypocretin-1) in narcoleptic patients
    Dalal, MA
    Schuld, A
    Haack, M
    Uhr, M
    Geisler, P
    Eisensehr, I
    Noachtar, S
    Pollmächer, T
    NEUROLOGY, 2001, 56 (12) : 1749 - 1751
12345