HER3 mediates acquired resistance to HER2-targeted therapy in esophageal adenocarcinoma

被引:1
|
作者
Ebbing, Eva A. [1 ]
Medema, Jan Paul [1 ]
Meijer, Sybren L. [1 ]
Krishnadath, Kausilia K. [1 ]
Henegouwen, Mark I. van Berge [1 ]
Bijlsma, Maarten F. [1 ]
van Laarhoven, Hanneke W. M. [1 ]
机构
[1] AMC, Amsterdam, Netherlands
关键词
D O I
10.1158/1538-7445.AM2015-350
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
350
引用
收藏
页数:1
相关论文
共 50 条
  • [1] Her2-Targeted Therapy Induces Autophagy in Esophageal Adenocarcinoma Cells
    Janser, Felice A.
    Adams, Olivia
    Buetler, Vanessa
    Schlaefli, Anna M.
    Dislich, Bastian
    Seiler, Christian A.
    Kroll, Dino
    Langer, Rupert
    Tschan, Mario P.
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 19 (10)
  • [2] HER3 MUTATIONS AFFECT TUMOR RESPONSE TO HER2-TARGETED THERAPIES
    不详
    CANCER DISCOVERY, 2021, 11 (09) : 2122 - 2122
  • [3] HER2 basal tumors have frequent mutation of HER3 and are more resistant to HER2-targeted therapy
    Varadan, Vinay
    Singh, Salendra
    Gilmore, Hannah
    Parsai, Shikha
    Somlo, George
    Abu-Khalaf, Maysa
    Sikov, William
    Harris, Lyndsay N.
    CANCER RESEARCH, 2016, 76
  • [4] A role for the pseudokinase HER3 in the acquired resistance against EGFR- and HER2-directed targeted therapy
    Claus, Jeroen
    Patel, Gargi
    Ng, Tony
    Parker, Peter J.
    BIOCHEMICAL SOCIETY TRANSACTIONS, 2014, 42 : 831 - 836
  • [5] Resistance mechanisms to HER2-targeted therapy in gastroesophageal adenocarcinoma: A systematic review
    Blange, Dionne
    Stroes, Charlotte I.
    Derks, Sarah
    Bijlsma, Maarten F.
    van Laarhoven, Hanneke W. M.
    CANCER TREATMENT REVIEWS, 2022, 108
  • [6] Molecular mechanisms of resistance to HER2-targeted therapy
    FJ Esteva
    Breast Cancer Research, 11
  • [7] Molecular mechanisms of resistance to HER2-targeted therapy
    Esteva, F. J.
    BREAST CANCER RESEARCH, 2009, 11 : S10 - S10
  • [8] HER2-targeted therapy is changing
    Matsumura, Noriomi
    INTERNATIONAL CANCER CONFERENCE JOURNAL, 2024, 13 (04): : 325 - 325
  • [9] HER2-Targeted Therapy in Osteosarcoma
    Gill, Jonathan
    Hingorani, Pooja
    Roth, Michael
    Gorlick, Richard
    CURRENT ADVANCES IN OSTEOSARCOMA: CLINICAL PERSPECTIVES: PAST, PRESENT AND FUTURE, 2ND EDITION, 2020, 1257 : 55 - 66
  • [10] AKT3 activation mediates resistance to HER2-targeted therapies in HER2-amplified breast cancer
    Sanz, F. Carmona
    Montemurro, F.
    Rossi, V.
    Verma, C.
    Berger, M.
    Baselga, J.
    Scaltriti, M.
    EUROPEAN JOURNAL OF CANCER, 2014, 50 : 27 - 28