Recurrent coronary disease in HIV-infected patients: role of drug-drug interactions

被引：10

作者：

Bravo, Iria ^{[1
]}

Alvarez, Hortensia ^{[2
]}

Marino, Ana ^{[2
]}

Clotet, Bonaventura ^{[3
,4
,5
,6
,7
]}

Molto, Jose ^{[3
,4
,5
]}

机构：

[1] Univ Hosp Ferrol, Dept Internal Med, Ave Residencia S-N, Ferrol 15405, A Coruna, Spain

[2] Univ Hosp Ferrol, Dept Internal Med, Infect Dis Unit, La Coruna, Spain

[3] Hosp Badalona Germans Trias & Pujol, Fundacio Lluita Sida, Badalona, Spain

[4] Hosp Badalona Germans Trias & Pujol, Dept Infect Dis, Badalona, Spain

[5] UAB, Barcelona, Spain

[6] Hosp Badalona Germans Trias & Pujol, Fundacio IrsiCaixa, Badalona, Spain

[7] Univ Cent Catalunya UVIC UCC, Univ Vic, Vic, Spain

来源：

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY | 2018年 / 84卷 / 07期

关键词：

coronary disease; drug interactions; HIV infection; PLATELET REACTIVITY; CONCISE GUIDE; PHARMACODYNAMICS; PHARMACOKINETICS; METAANALYSIS;

D O I：

10.1111/bcp.13583

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Cardiovascular disease represents a leading comorbidity in HIV populations. Different factors may contribute to the recurrence of cardiovascular events in HIV-infected patients. Here, we describe two patients with HIV infection and an acute coronary syndrome who developed in-stent thrombosis after a percutaneous revascularization procedure. Also, we discuss the potential role of drug interactions between antiretroviral and antiplatelet treatments as a contributing factor for recurrent coronary disease in HIV-infected patients.

引用

页码：1617 / 1619

页数：3

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