Ellipsometric surface plasmon resonance

被引：10
|
作者：
Hsu, Wei-Liang [1 ]
Lee, Shu-Sheng [2 ]
Lee, Chih-Kung [1 ,3 ,4 ]
机构：
[1] Natl Taiwan Univ, Inst Appl Mech, Taipei 10617, Taiwan
[2] Natl Taiwan Ocean Univ, Dept Syst Engn & Naval Architecture, Chilung 20224, Taiwan
[3] Natl Taiwan Univ, Dept Engn Sci & Ocean Engn, Taipei 10617, Taiwan
[4] Ind Technol Res Inst, Hsinchu 31040, Taiwan
来源：
JOURNAL OF BIOMEDICAL OPTICS | 2009年 / 14卷 / 02期
关键词：
multifunctional optical biochip system; biosensor; surface plasmon resonance; ellipsometry; BIOSENSOR; FILMS; ASSAY; SPR;
D O I：
10.1117/1.3116713
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
We develop a new multifunctional optical biochip system that integrates an ellipsometer with a surface plasmon resonance (SPR) feature. This newly developed biochip biosensor, which we call ESPR for an ellipsometric SPR, provides us with a system to retrieve detailed information such as the optical properties of immobilized biomolecular monolayers, surface concentration variations of biomedical reactions, and kinetic affinity between biomolecules required for further biotech analysis. Our ESPR can also serve as both a research and development tool and a manufacturing tool for various biomedical applications. (C) 2009 Society of Photo-Optical Instrumentation Engineers. [DOI: 10.1117/1.3116713]
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页数：8
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