Reactions of 1,2-& 1,4-dihydropyridines

被引:15
|
作者
Singh, Sunil K. [1 ]
Sharma, Vivek K. [2 ]
机构
[1] Univ Delhi, Kirori Mal Coll, Dept Chem, Delhi 110007, India
[2] Univ Delhi, Dept Chem, Delhi 110007, India
关键词
1,2-1,4-Dihydropyridines; aromatization; cycloaddition; diamination; oxidation; oxyselenation; photodimerisation; rearrangement; DIELS-ALDER REACTION; ORGANOCATALYTIC TRANSFER HYDROGENATION; ASYMMETRIC TRANSFER HYDROGENATION; ROOM-TEMPERATURE AROMATIZATION; CONVENIENT OXIDIZING-AGENT; HIGH-YIELD OXIDATION; ONE-POT SYNTHESIS; HANTZSCH 1,4-DIHYDROPYRIDINES; EFFICIENT OXIDATION; ORGANIC AZIDES;
D O I
10.2174/1385272819666140201003050
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
This review provides a comprehensive compilation of available literature concerning the reactions of 1,2- & 1,4-dihydropyridines, which have opened new frontiers in the area of synthetic and medicinal chemistry. These reactions mainly include cycloaddition, 1,3-Dipolar cycloaddition, alkoxy halogenation, diamination, hydroxyamination, oxidation, hydroxylation, photooxygenation reaction, nucleophilic addition, cyclization, electrophilic substitution, multicomponent reactions (MCRs) and rearrangement reactions. 1,4-Dihydropyridine has also been used in hydrogen transfer reactions as a synthetic NADH model for the reduction of several important molecules in excellent yields.
引用
收藏
页码:1159 / 1207
页数:49
相关论文
共 50 条
  • [1] Synthesis, utility and medicinal importance of 1,2-& 1,4-dihydropyridines
    Sharma, Vivek K.
    Singh, Sunil K.
    RSC ADVANCES, 2017, 7 (05): : 2682 - 2732
  • [2] REACTIONS OF 1,4-DIHYDROPYRIDINES
    SAUSINSH, A
    DUBUR, G
    KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 1993, (05): : 579 - 612
  • [3] REACTIONS OF 1,4-DIHYDROPYRIDINES
    SAUSINS, A
    DUBURS, G
    HETEROCYCLES, 1988, 27 (01) : 291 - 314
  • [4] SYNTHESIS OF 1,2-DIHYDROPYRIDINES AND 1,4-DIHYDROPYRIDINES
    FOWLER, FW
    JOURNAL OF ORGANIC CHEMISTRY, 1972, 37 (09): : 1321 - &
  • [5] SYNTHESIS OF 1,4-DIHYDROPYRIDINES BY CYCLOCONDENSATION REACTIONS
    SAUSINS, A
    DUBURS, G
    HETEROCYCLES, 1988, 27 (01) : 269 - 289
  • [6] SYNTHESIS OF 1,4-DIHYDROPYRIDINES IN THE CYCLOCONDENSATION REACTIONS
    SAUSINSH, AE
    DUBURS, GY
    KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 1992, (04): : 435 - 467
  • [7] ADDITION REACTIONS UPON 1,4-DIHYDROPYRIDINES
    Teotia, Anil Kumar
    Kumar, Rakesh
    Chandra, Ramesh
    HETEROCYCLIC LETTERS, 2011, 1 (03): : 227 - 233
  • [8] SOME SUBSTITUTION AND HETEROCYCLIZATION REACTIONS OF 1,4-DIHYDROPYRIDINES
    SKRASTINSH, IP
    DUBURS, GY
    KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 1992, (06): : 781 - 791
  • [9] Iodocyclization of 1,4-dihydropyridines
    Lavilla, R
    Coll, O
    Nicolàs, M
    Bosch, J
    TETRAHEDRON LETTERS, 1998, 39 (28) : 5089 - 5092
  • [10] PHOTOOXIDATION OF 1,4-DIHYDROPYRIDINES
    MITSUNOBU, O
    WADA, M
    MASUDA, H
    MATSUMOT.S
    BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1972, 45 (05) : 1453 - +