No association between the Clara cell secretory protein (CC16) gene polymorphism and personality traits

被引：0

作者：

Tochigi, Mamoru

Otowa, Takeshi

Hibino, Hiroyuki

Kato, Chieko

Marui, Tetsuya

Ohtani, Toshiyuki

Umekage, Tadashi

Kato, Nobumasa

Sasaki, Tsukasa

机构：

[1] Univ Tokyo, Grad Sch Med, Dept Neuropsychiat, Bunkyo Ku, Tokyo 1138655, Japan

[2] Univ Tokyo, Hlth Serv Ctr, Bunkyo Ku, Tokyo 1138655, Japan

来源：

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY | 2006年 / 30卷 / 06期

关键词：

Clara cell secretory protein (CC16); personality traits; the Revised NEO Personality Inventory (NEO PI-R); the State-Trait Anxiety Inventory (STAI);

D O I：

10.1016/j.pnpbp.2006.04.019

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Clara cell secretory protein (CC16) is an anti-inflammatory protein expressed in the respiratory tract. Several studies have suggested the association between CC16 and mental disturbances, such as schizophrenia, depression, and post-traumatic stress disorder. In the present study, we investigated the association between the CC16 gene A38G polymorphism and personality traits in 214 healthy Japanese subjects. Personality traits were evaluated by using the Revised NEO Personality Inventory (NEO PI-R) and the State-Trait Anxiety Inventory (STAI). As a result, no significant association was observed between the genotypes and the scores of the NEO PI-R. or the STAI. The present results suggest that CC16 may not have a major role in the development of personality traits. (c) 2006 Elsevier Inc. All rights reserved.

引用

页码：1122 / 1124

页数：3

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