Synthesis of some new cyanopyrans and cyanopyridines and their biological activities

被引：0
|
作者：
Popat, KH [1 ]
Kachhadia, VV [1 ]
Nimavat, KS [1 ]
Joshi, HS [1 ]
机构：
[1] Saurashtra Univ, Dept Chem, Rajkot 360005, Gujarat, India
来源：
JOURNAL OF THE INDIAN CHEMICAL SOCIETY | 2004年 / 81卷 / 02期
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D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Chalcones 1-aryl-3-m-chlorophenyl-2-propene-1-ones, 1a-j, underwent Michael addition on refluxing with malononitrile in the presence of pyridine and ammonium acetate in ethanol to give compounds 2-amino-3-cyano-4-(3'-chlorophenyl)-6-(4-phenyl)-pyran, 2a-j and 2-amino-3-cyano-4-(3'-chlorophenyl)-6-(4-phenyl)-pyridine, 3a-j, respectively. The newly synthesized compounds have been screened for their anticancer, antitubercular and antimicrobial activities.
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页码：157 / 159
页数：3
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