Asymmetric allylboration of cyclic imines and applications to alkaloid synthesis

被引:124
|
作者
Wu, T. Robert [1 ]
Chong, J. Michael [1 ]
机构
[1] Univ Waterloo, Guelph Waterloo Ctr Grad Work Chem & Biochem, Dept Chem, Waterloo, ON N2L 3G1, Canada
关键词
D O I
10.1021/ja0636791
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Treatment of cyclic imines with 3,3′-disubstituted binaphthol modified allylboronates provides the expected allylated products in good yields and with high stereoselectivities (91-99% ee). The products may be readily transformed into various alkaloids. Copyright © 2006 American Chemical Society.
引用
收藏
页码:9646 / 9647
页数:2
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