Olanzapine improves chorea inpatients with Huntington's disease

Introduction. The main treatment for choreatic movements associated to Huntington's disease are the neuroleptic drugs, however, its use causes long-term troubles. Case reports. We describe two patients with a predominantly choreic Huntington's disease, who experience improvement of choreatic movements after introduction of olanzapine to their treatment, being this drug well tolerated. Conclusions. The improvement of chorea suggests that olanzapine has a dopaminergic D-2 receptors blocking action.