Feedback Regulation of Lac Repressor Expression in Escherichia coli

被引:8
|
作者
Oehler, Stefan [1 ]
机构
[1] IMBB FORTH, GR-70013 Iraklion, Crete, Greece
关键词
OPERON; OPERATOR; INDUCTION; COMPLEX;
D O I
10.1128/JB.00427-09
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Negative feedback regulation, mediated through repressor binding site O3, which overlaps the lacI gene, could explain the robustness of the weak expression of Lac repressor. Significant autorepression of Lac repressor has never been ruled out. In the work presented here, the degree of autoregulation of Lac repressor was determined. It is negligible.
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页码:5301 / 5303
页数:3
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