Quality Control and Cell Line Cross-Contamination: An Old Problem that Continues To Fester

被引：0
|
作者：
Masters, John R. [1 ]
机构：
[1] UCL, Div Surg & Intervent Sci, London, England
来源：
PROCEEDINGS OF THE 21ST ANNUAL MEETING OF THE EUROPEAN SOCIETY FOR ANIMAL CELL TECHNOLOGY (ESACT), 2009 | 2012年 / 5卷
关键词：
T24; BLADDER-CARCINOMA; TARGET GENE; SUPPRESSION; CANCER;
D O I：
10.1007/978-94-007-0884-6_35
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Cell line misidentification results in the use of a model system derived from a different species or tissue or individual to that claimed. The accidental and fraudulent use of misidentified cell lines has contaminated a significant proportion of the scientific literature for over 50 years. Cheap and reproducible methods such as STR profiling are available to identify the problem and authenticate individual cell lines. Every laboratory needs to adopt the new standard being developed by the ATCC.
引用
收藏
页码：235 / 239
页数：5
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