A New Look at TCF and β-Catenin through the Lens of a Divergent C-elegans Wnt Pathway

被引：77
|
作者：
Phillips, Bryan T. [1 ,2 ]
Kimble, Judith [1 ,2 ]
机构：
[1] Univ Wisconsin, Dept Biochem, Madison, WI 53706 USA
[2] Univ Wisconsin, Howard Hughes Med Inst, Madison, WI 53706 USA
来源：
DEVELOPMENTAL CELL | 2009年 / 17卷 / 01期
关键词：
NEMO-LIKE-KINASE; ASYMMETRIC CELL-DIVISION; RECIPROCAL ASYMMETRY; SIGNALING PATHWAYS; POLARITY SIGNALS; PROTEIN-KINASE; MAP KINASE; POP-1; GENE; FATE;
D O I：
10.1016/j.devcel.2009.07.002
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The canonical Wnt/beta-catenin pathway is extensively characterized, broadly conserved, and clinically important. In this review, we describe the C. elegans Wnt/beta-catenin asymmetry pathway and suggest that some of its unusual features may have important implications for the canonical Wnt/beta-catenin pathway.
引用
收藏
页码：27 / 34
页数：8
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