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Acid, weakly acidic and non-acid gastro-oesophageal reflux: differences, prevalence and clinical relevance
被引:47
|作者:
Sifrim, D
[1
]
机构:
[1] Catholic Univ Louvain, Ctr Gastroenterol Res, B-3000 Louvain, Belgium
关键词:
gastro-oesophageal reflux;
pH-metry;
impedance;
D O I:
10.1097/00042737-200409000-00002
中图分类号:
R57 [消化系及腹部疾病];
学科分类号:
摘要:
patients with gastro-oesophageal reflux disease (GORD), oesophageal symptoms and mucosal damage traditionally are related to acid-reflux episodes with pH lower than 4. Oesophageal or extra-oesophageal symptoms of GORD may also be associated with less acidic reflux (pH 4-7). New methodologies have evolved to complement pH monitoring for characterisation of less acidic gastro-oesophageal reflux. This review will focus on definition, detection, pathophysiology and symptom association of weakly acidic and non-acid reflux, in both adult and paediatric populations.
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页码:823 / 830
页数:8
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