miR in CLL: more than mere markers of prognosis?

被引：0

作者：

Kater, Arnon P. ^{[1
]}

Eldering, Eric ^{[1
]}

机构：

[1] Univ Amsterdam, Acad Med Ctr, NL-1012 WX Amsterdam, Netherlands

来源：

BLOOD | 2014年 / 124卷 / 01期

关键词：

MICRORNAS;

D O I：

10.1182/blood-2014-05-574152

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In this issue of Blood, Mraz et al show that microRNA-150 (miR-150) is the most abundantly expressed miR in chronic lymphocytic leukemia (CLL) and affects the threshold for B-cell receptor (BCR) signaling by repressing expression levels of GAB1 and FOXP1. This functional link might explain the described association between expression levels of miR-150 and prognosis.(1)

引用

页码：2 / 4

页数：5

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