Phenomenological simulation of self-organization of microtubule driven by dynein c

被引：1
|
作者：
Chen, Q. [1 ]
Li, D. Y. [1 ,2 ]
Oiwa, K. [3 ]
机构：
[1] Univ Alberta, Dept Biomed Engn, Edmonton, AB T6G 2V2, Canada
[2] Univ Alberta, Dept Chem & Mat Engn, Edmonton, AB T6G 2V4, Canada
[3] Natl Inst Informat & Commun Technol, Kobe Adv ICT Res Ctr, Nishi Ku, Kobe, Hyogo 6512492, Japan
来源：
JOURNAL OF CHEMICAL PHYSICS | 2009年 / 130卷 / 21期
关键词：
molecular biophysics; Monte Carlo methods; nanobiotechnology; probability; proteins; self-assembly; ELECTRON-MICROSCOPY; CYTOPLASMIC DYNEIN; MOTOR PROTEIN; KINESIN; TRACKS; CENTROSOME; COMPLEX; BINDING;
D O I：
10.1063/1.3139300
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
It was recently noticed that in vitro motility assays, driven by random distributed dynein c, microtubules could form self-organized circular patterns, which could be of importance to the design of nanobiomechanical machines. In order to determine key parameters that control the self-organized movement of microtubules, a phenomenological modeling study taking account of the microtubule joining probability distribution and microtubule bias was conducted to investigate the self-organization of microtubules driven by dynein motors.
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页数：8
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