Genetics of cardiac repolarization

被引：5
|
作者：
Shah, Svati H. [1 ]
Pitt, Geoffrey S. [1 ]
机构：
[1] Duke Univ, Med Ctr, Dept Med, Div Cardiol, Durham, NC 27710 USA
来源：
NATURE GENETICS | 2009年 / 41卷 / 04期
关键词：
LONG-QT SYNDROME; INTERVAL; MORTALITY; VARIANTS;
D O I：
10.1038/ng0409-388
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
Prolongation of the electrocardiographic QT interval, a measure of cardiac repolarization, is associated with arrhythmogenic disorders and is a risk factor for sudden cardiac death. Two genome-wide association studies (GWAS) of variation in the QT interval in population-based cohorts now report association with variants in a subset of ion channel genes and other new associations.
引用
收藏
页码：388 / 389
页数：3
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