Targeting lysosomal homeostasis in ovarian cancer through drug repurposing

被引：0
|
作者：
Marastoni, Stefano [1 ]
Pesic, Aleksandra [1 ]
Nair, Sree Narayanan [1 ]
Li, Zhu Juan [2 ]
Madani, Ali [1 ]
Haibe-Kains, Benjamin [1 ]
Wouters, Bradly G. [1 ]
Joshua, Anthony [3 ]
机构：
[1] Univ Hlth Network, Toronto, ON, Canada
[2] Janssen Inc, Toronto, ON, Canada
[3] Kinghorn Canc Ctr, Sydney, NSW, Australia
来源：
CANCER RESEARCH | 2020年 / 80卷 / 16期
关键词：
D O I：
10.1158/1538-7445.AM2020-3401
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
3401
引用
收藏
页数：2
相关论文
共 50 条
  • [1] Repurposing Itraconazole and Hydroxychloroquine to Target Lysosomal Homeostasis in Epithelial Ovarian Cancer
    Marastoni, Stefano
    Madariaga, Ainhoa
    Pesic, Aleksandra
    Nair, Sree Narayanan
    Li, Zhu Juan
    Shalev, Zvi
    Ketela, Troy
    Colombo, Ilaria
    Mandilaras, Victoria
    Cabanero, Michael
    Bruce, Jeff P.
    Li, Xuan
    Garg, Swati
    Wang, Lisa
    Chen, Eric X.
    Gill, Sarbjot
    Dhani, Neesha C.
    Zhang, Wenjiang
    Pintilie, Melania
    Bowering, Valerie
    Koritzinsky, Marianne
    Rottapel, Robert
    Wouters, Bradly G.
    Oza, Amit M.
    Joshua, Anthony M.
    Lheureux, Stephanie
    CANCER RESEARCH COMMUNICATIONS, 2022, 2 (05): : 293 - 306
  • [2] Targeting Glucosylceramide Synthase: Innovative Drug Repurposing Strategies for Lysosomal Diseases
    Canini, Giorgia
    Mazzinelli, Elena
    Nocca, Giuseppina
    Lattanzi, Wanda
    Arcovito, Alessandro
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2025, 26 (05)
  • [3] Targeting Inflammation in Non-Small Cell Lung Cancer through Drug Repurposing
    Rajasegaran, Thiviyadarshini
    How, Chee Wun
    Saud, Anoosha
    Ali, Azhar
    Lim, Jonathan Chee Woei
    PHARMACEUTICALS, 2023, 16 (03)
  • [4] Artemisinins as a novel anti-cancer therapy: Targeting a global cancer pandemic through drug repurposing
    Augustin, Yolanda
    Staines, Henry M.
    Krishna, Sanjeev
    PHARMACOLOGY & THERAPEUTICS, 2020, 216
  • [5] Targeting Zika Virus Infection Through Drug Repurposing Screen
    不详
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 2017, 101 (01) : 13 - 13
  • [6] Targeting notch signaling pathway in breast cancer stem cells through drug repurposing approach
    Pathak, Yamini
    Camps, Ihosvany
    Mishra, Amaresh
    Tripathi, Vishwas
    MOLECULAR DIVERSITY, 2023, 27 (06) : 2431 - 2440
  • [7] Targeting notch signaling pathway in breast cancer stem cells through drug repurposing approach
    Yamini Pathak
    Ihosvany Camps
    Amaresh Mishra
    Vishwas Tripathi
    Molecular Diversity, 2023, 27 : 2431 - 2440
  • [8] EXPLOITING VULNERABILITIES IN OVARIAN CANCER BY TARGETING PROTEIN HOMEOSTASIS
    Chien, J.
    INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2017, 27 : 1461 - 1461
  • [9] Editorial: Cancer neuroscience: Drug repurposing targeting the innervated niche
    Jin, Ming-Zhu
    Gao, Xing-Chun
    Jin, Wei-Lin
    FRONTIERS IN PHARMACOLOGY, 2023, 14
  • [10] Drug repurposing screen targeting PARP identifies cytotoxic activity of efavirenz in high-grade serous ovarian cancer
    Matthews, Bayley
    Wong-Brown, Michelle
    Liu, Dongli
    Yee, Christine
    Dickson, Kristie-Ann
    Schneider, Jennifer
    Islam, Saiful
    Head, Richard
    Martin, Jennifer H.
    Ford, Caroline E.
    Marsh, Deborah J.
    Bowden, Nikola A.
    MOLECULAR THERAPY ONCOLOGY, 2024, 32 (04):
12345