A facile and environmental friendly strategy for the synthesis of N-methoxyquinolin-2(1H)-ones

被引：6
|
作者：
Gao, Xianying [1 ]
Liang, Apeng [1 ]
Li, Jingya [2 ,3 ]
Zou, Dapeng [1 ,2 ]
Wu, Yangjie [1 ]
Wu, Yusheng [2 ,4 ]
机构：
[1] Zhengzhou Univ, Coll Chem & Mol Engn, Zhengzhou 450052, Peoples R China
[2] Collaborat Innovat Ctr New Drug Res & Safety Eval, Zhengzhou, Henan Province, Peoples R China
[3] Tetranov Biopharm LLC, 75 Daxue Rd, Zhengzhou 450052, Peoples R China
[4] Tetranov Int Inc, 100 Jersey Ave,Suite A340, New Brunswick, NJ 08901 USA
来源：
TETRAHEDRON LETTERS | 2017年 / 58卷 / 20期
关键词：
N-methoxyquinolin-2(1H)-ones; N-methoxyquinoline-l-ium; tetrafluoroborate salts; N-protected; C-H ACTIVATION; CATALYZED CARBONYLATIVE ANNULATION; N BOND FORMATION; METAL-FREE; OXIDATIVE ANNULATION; WEINREB AMIDES; 2-QUINOLINONES; HETEROCYCLES; QUINOLINONES; AMIDATION;
D O I：
10.1016/j.tetlet.2017.03.001
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A facile and environmental friendly protocol for the construction of N-methoxyquinolin-2(1H)-ones was developed using a stable and easily available N-methoxyquinoline-l-ium tetrafluoroborate as starting material. Due to the mild reaction conditions, a broad range of N-methoxyquinolin-2(1H)-ones with different functional groups have been prepared in reasonable yields. (C) 2017 Elsevier Ltd. All rights reserved.
引用
收藏
页码：1917 / 1920
页数：4
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