Tropisetron-dexamethasone combination for carboplatin-induced emesis

被引：0
|
作者：
Pronzato, P
Ghio, E
Losardo, PL
Vaira, F
Vigani, A
机构：
来源：
ONCOLOGY REPORTS | 1996年 / 3卷 / 06期
关键词：
tropisetron; dexamethasone; carboplatin; emesis;
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Sixty-six patients being given polychemotherapy schedules including carboplatin entered an antiemetic protocol with tropisetron and dexamethasone at the dose of 5 mg and 8 mg respectively. A complete response (no episodes of vomiting) and a major response (less than or equal to 2 episodes of vomiting) were observed in 55 and and 7 patients respectively. It is concluded that the tropisetron-dexamethasone combination is highly active in the control of emesis induced by conventional doses of carboplatin in combination.
引用
收藏
页码：1179 / 1181
页数：3
相关论文
共 50 条
  • [1] Efficacy of ondansetron and metoclopramide (with dexamethasone): In the prevention of carboplatin-induced emesis
    duBois, A
    Andersson, H
    Lahousen, M
    Kitchener, H
    Pinter, T
    Capstick, V
    McKenna, CJ
    [J]. EUROPEAN JOURNAL OF CANCER, 1995, 31A : 1216 - 1216
  • [2] PATTERN OF CARBOPLATIN-INDUCED EMESIS
    DUBOIS, A
    VACH, W
    CRAMERGIRAUD, U
    THOMSSEN, C
    GLAUBITZ, M
    FIOLA, M
    AUGENER, W
    BARTSCH, W
    BERGMANN, F
    BIERBAUM, W
    KRAPP, J
    BONING, L
    BONGARTZ, U
    BRUNTSCH, U
    VONBULTZINGSLOWEN, F
    DIETL, J
    FUGER, T
    FULLE, HH
    GATZEMEIER, U
    GROPP, C
    HARTLAPP, H
    HERSCHLEIN, HJ
    HOLTKAMP, W
    HURST, U
    JANICKE, F
    KAUKEL, E
    KLEEBERG, U
    ENGEL, E
    KRAFFT, W
    KUHNLE, H
    LINDEMANN, H
    MARSCHNER, N
    MEERPOHL, HG
    NIEDERLE, N
    OSIEKA, R
    PLANKER, M
    RIESS, H
    SCHMIDT, M
    SCHMOLL, HJ
    SCHUNEMANN, H
    WEINGARTJESSE, B
    WEITZEL, H
    WESTERHAUSEN, M
    WINKELMANN, M
    [J]. ANTI-CANCER DRUGS, 1995, 6 (05) : 645 - 651
  • [3] ANTIEMETIC EFFICACY OF ALPRAZOLAM IN CARBOPLATIN-INDUCED EMESIS
    TSAVARIS, N
    TSOUTSOS, H
    BACOYANNIS, C
    MYLONAKIS, N
    KARVOUNIS, N
    KOZATSANIHALIVIDI, D
    TSAROUCHANOUTSOU, E
    KLINAKI, A
    KOSMIDIS, P
    [J]. CHEMOTHERAPY, 1991, 37 (05) : 364 - 370
  • [4] Control of carboplatin-induced emesis with a fixed low dose of granisetron (0.5 mg) plus dexamethasone
    Markman, M
    Kennedy, A
    Webster, K
    Kulp, B
    Peterson, G
    Belinson, J
    [J]. GYNECOLOGIC ONCOLOGY, 1996, 60 (03) : 435 - 437
  • [5] TROPISETRON (NAVOBAN) ALONE AND IN COMBINATION WITH DEXAMETHASONE IN THE PREVENTION OF CHEMOTHERAPY-INDUCED EMESIS - THE NORDIC EXPERIENCE
    SORBE, BG
    [J]. SEMINARS IN ONCOLOGY, 1994, 21 (05) : 20 - 26
  • [6] Pathophysiology, severity, pattern, and risk factors for carboplatin-induced emesis
    duBois, A
    Vach, W
    Kiechle, M
    CramerGiraud, U
    Meerpohl, HG
    [J]. ONCOLOGY, 1996, 53 : 46 - 50
  • [7] Low-dose intravenous ondansetron (8 mg) plus dexamethasone: An effective regimen for the control of carboplatin-induced emesis
    Markman, M
    Kennedy, A
    Webster, K
    Peterson, G
    Kulp, B
    Belinson, J
    [J]. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 1997, 123 (04) : 224 - 226
  • [8] Low-dose intravenous ondansetron (8 mg) plus dexamethasone: An effective regimen for the control of carboplatin-induced emesis
    Markman M.
    Kennedy A.
    Webster K.
    Peterson G.
    Kulp B.
    Belinson J.
    [J]. Journal of Cancer Research and Clinical Oncology, 1997, 123 (4) : 224 - 226
  • [9] TROPISETRON ALONE OR IN COMBINATION WITH DEXAMETHASONE FOR THE PREVENTION AND TREATMENT OF EMESIS INDUCED BY NON-CISPLATIN CHEMOTHERAPY - A RANDOMIZED TRIAL
    ADAMS, M
    SOUKOP, M
    BARLEY, V
    YOSEF, H
    ANDERSON, N
    BOESEN, E
    TRASK, CW
    RUFENACHT, E
    DEBRUIJN, KM
    [J]. ANTI-CANCER DRUGS, 1995, 6 (04) : 514 - 521
  • [10] A study evaluating the efficacy and tolerability of tropisetron in combination with dexamethasone in the prevention of delayed platinum-induced nausea and emesis
    Sorbe, BG
    Berglind, AM
    Andersson, H
    Boman, K
    Högberg, T
    Hallgren, M
    Schmidt, M
    [J]. CANCER, 1998, 83 (05) : 1022 - 1032
12345