Spina bifida: A multidisciplinary perspective on a many-faceted condition

被引：7
|
作者：
Fieggen, G. [1 ,2 ]
Fieggen, K. [2 ,3 ]
Stewart, C. [4 ,5 ]
Padayachy, L. [1 ,2 ]
Lazarus, J. [2 ,6 ]
Donald, K. [2 ,7 ]
Dix-Peek, S. [2 ,8 ]
Toefy, Z. [2 ]
Figaji, A. [1 ,2 ]
机构：
[1] Univ Cape Town, Div Neurosurg, ZA-7925 Cape Town, South Africa
[2] Red Cross War Mem Childrens Hosp, Spina Bifida Clin, Cape Town, South Africa
[3] Univ Cape Town, Div Med Genet, ZA-7925 Cape Town, South Africa
[4] Univ Cape Town, Dept Obstet & Gynaecol, Cape Town, South Africa
[5] Groote Schuur Hosp, Fetal Med Unit, ZA-7925 Cape Town, South Africa
[6] Univ Cape Town, Div Urol, ZA-7925 Cape Town, South Africa
[7] Univ Cape Town, Div Dev Paediat, ZA-7925 Cape Town, South Africa
[8] Univ Cape Town, Div Orthopaed Surg, ZA-7925 Cape Town, South Africa
来源：
SAMJ SOUTH AFRICAN MEDICAL JOURNAL | 2014年 / 104卷 / 03期
关键词：
NEURAL-TUBE DEFECTS; FOLIC-ACID; PREVALENCE; ADULT;
D O I：
10.7196/SAMJ.8079
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Open spina bifida or myelomeningocele (SBM) is the most common birth defect involving the central nervous system, second only in incidence to congenital cardiac disease. Outcomes in this disorder were poor until the mid-20th century, when modern neurosurgical techniques (closing the lesion and treating hydrocephalus) and treatment for the neuropathic bladder addressed the major causes of mortality, although SBM may still be poorly treated in the developing world. Initial management - or mismanagement - has a profound impact on survival and long-term quality of life.
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页码：213 / 217
页数：5
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