Action of nitrile hydratase from Rhodococcus rhodochrous IFO 15564 on derivatives of 2,5-anhydro-D-allononitrile

被引：7
|
作者：
Yokoyama, M [1 ]
Nakatsuka, Y [1 ]
Sugai, T [1 ]
Ohta, H [1 ]
机构：
[1] KEIO UNIV, DEPT CHEM, KOHOKU KU, YOKOHAMA, KANAGAWA 223, JAPAN
来源：
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 1996年 / 60卷 / 09期
关键词：
Rhodococcus rhodochrous IFO 15564; nitrile hydratase; 2,5-anhydro-D-allononitrile; 2,5-anhydro-D-allonamide; hydantocidin;
D O I：
10.1271/bbb.60.1540
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The conversion of 2,5-anhydro-D-allononitrile derivatives by a nitrile hydratase from Rhodococcus rhodochrous IFO 15564 was studied. The activity of the enzyme was strongly effected hg the steric bulkiness of the substituents at the 3-position of the substrates, and the corresponding amides were obtained in high yields from the nitriles with free hydroxyl groups at the 3- and 4-positions.
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页码：1540 / 1542
页数：3
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