Prevalence and phylogenic study of human T-lymphotropic virus 1 in patients with thalassemia in the northeast of Iran

被引：8
|
作者：
Abedi, Farshid [1 ,2 ]
Mozhgani, Sayed-Hamidreza [3 ]
Rahimzadegan, Marzieh [2 ]
Gudarzi, Hoda [3 ]
Valizadeh, Narges [4 ]
Rezaee, Seyed Abdolrahim [4 ]
机构：
[1] Birjand Univ Med Sci, Dept Infect Dis, Birjand, Iran
[2] Mashhad Univ Med Sci, Dept Infect Dis, Mashhad, Iran
[3] Univ Tehran Med Sci, Sch Publ Hlth, Dept Virol, Tehran, Iran
[4] Mashhad Univ Med Sci, Inflammat & Inflammatory Dis Div, Immunol Res Ctr, Mashhad, Iran
来源：
FUTURE VIROLOGY | 2017年 / 12卷 / 05期
关键词：
HTLV-1; phylogeny; prevalence; Iran; thalassemia; HTLV-I INFECTION; HEPATITIS-B; SEROEPIDEMIOLOGY; SEROPREVALENCE; POPULATION; EPIDEMIOLOGY; TRANSMISSION; RISK;
D O I：
10.2217/fvl-2016-0107
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
This study aimed to investigate the frequency and phylogenetic distribution of human T-lymphotropic virus type 1 (HTLV-1) in thalassemia cases. Methods: Between 2006 and 2013, a total of 100 thalassemic individuals were investigated for HTLV-1 infections. Results: Four people (4%) were reactive for HTLV antibodies. No considerable correlation was seen between factors such as age, blood transfusion history, surgery, marital status, gender and blood types. All HTLV-1 sequences belonged to the transcontinental (A) subgroup in the cosmopolitan (a) subtype. Conclusion: In addition to phylogenetic distribution, our results demonstrate that the prevalence of HTLV-1 infection among thalassemia patients in Mashhad is higher than that of previous studies.
引用
收藏
页码：253 / 258
页数：6
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