Preoperative imaging staging of rectal cancer

Carcinomas of the rectum are associated with a significant local and distant recurrence rate. Not all patients are appropriate candidates for preoperative radiation therapy. Preoperative identification of those most likely to benefit from neoadjuvant therapy is important. There is no general consensus on the role of endorectal ultrasonography, computed tomography (CT), and magnetic resonance imaging (MRI) in staging patients with rectal cancer. Although the tumor stage is an important prognostic factor, preoperative assessment is associated with prediction of the circumferential resection margin. Newer developments such as coils, sequences and gradients in MRI, evolution of multidetector CT and new contrast media, allow for an algorithm selection aiming at the best diagnostic options for patients. The present review will discuss the current role of the various imaging modalities in staging carcinomas of the rectum. Copyright (c) 2007 S. Karger AG, Basel