Synthesis and functionalization of 4-arylamino-2-pyridone derivatives

被引：6
|
作者：
Tugusheva, N. Z.
Alekseeva, L. M.
Shashkov, A. S.
Chernyshev, V. V.
Granik, V. G.
机构：
[1] State Res Ctr Antibiot, Moscow 117105, Russia
[2] Russian Acad Sci, ND Zelinskii Organ Chem Inst, Moscow 119991, Russia
[3] Moscow MV Lomonosov State Univ, Dept Chem, Moscow 119992, Russia
来源：
RUSSIAN CHEMICAL BULLETIN | 2006年 / 55卷 / 08期
关键词：
amide acetals; 3-cyano-2-oxo-5-R-4-(phenylamino)-1,2-dihydropyridines; 4-arylamino-3,5-dicyanopyridines; acidic hydrolysis; NMR spectroscopy; X-ray diffraction analysis;
D O I：
10.1007/s11172-006-0443-4
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
New approaches to the synthesis of the previously unknown pyrimidine, 4-amino-2-pyridone, and 4-aminopyridine derivatives were developed based on the reactions of enaminoamides with dimethylformamide dimethyl acetal. New structural modifications of 4-amino-2-pyridone derivatives were performed. Numerous compounds of this type, which are of interest for biological studies, were prepared.
引用
收藏
页码：1475 / 1486
页数：12
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