Approaches to the treatment of disease induced by chikungunya virus

被引:0
|
作者
Bettadapura, Jayaram [1 ]
Herrero, Lara J. [1 ]
Taylor, Adam [1 ]
Mahalingam, Suresh [1 ]
机构
[1] Griffith Univ, Inst Glyc, Emerging Viruses & Inflammat Res Grp, Nathan, Qld 4222, Australia
基金
英国医学研究理事会;
关键词
Antivirals; arthralgia; chikungunya; CHIKV; vaccines; MOUSE MODEL; ANTIVIRAL ACTIVITY; VACCINE; ARTHRITIS; REPLICATION; INHIBITION; INFECTION; IMMUNOGENICITY; IDENTIFICATION; EPIDEMIC;
D O I
暂无
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Chikungunya virus, a re-emerging mosquito-borne alphavirus, causes fever, rash and persistent arthralgia/arthritis in humans. Severe outbreaks have occurred resulting in infections of millions of people in Southeast Asia and Africa. Currently there are no antiviral drugs or vaccines for prevention and treatment of chikungunya infections. Herein we report the current status of research on antiviral drugs and vaccines for chikungunya virus infections.
引用
收藏
页码:762 / 765
页数:4
相关论文
共 50 条
  • [1] Fingolimod treatment abrogates chikungunya virus-induced arthralgia
    Teo, Teck-Hui
    Chan, Yi-Hao
    Lee, Wendy W. L.
    Lum, Fok-Moon
    Amrun, Siti Naqiah
    Her, Zhisheng
    Rajarethinam, Ravisankar
    Merits, Andres
    Rotzschke, Olaf
    Renia, Laurent
    Ng, Lisa F. P.
    SCIENCE TRANSLATIONAL MEDICINE, 2017, 9 (375)
  • [2] Chikungunya virus induced myocarditis
    Mendoza, I.
    Morr, I.
    Mendoza, I.
    Gonzalez, K.
    Villalobos, I.
    Meza, Y.
    Morr, C.
    Morr, C.
    Marques, J.
    EUROPEAN HEART JOURNAL, 2015, 36 : 501 - 501
  • [3] Chikungunya virus and arthritic disease
    Burt, Felicity
    Chen, Weiqiang
    Mahalingam, Suresh
    LANCET INFECTIOUS DISEASES, 2014, 14 (09): : 789 - 790
  • [4] New Approaches to Chikungunya Virus Vaccine Development
    Garcia, Alexis
    Diego, Lema
    Judith, Barroso
    RECENT PATENTS ON INFLAMMATION & ALLERGY DRUG DISCOVERY, 2015, 9 (01) : 31 - 37
  • [5] Interleukin-17 Contributes to Chikungunya Virus-Induced Disease
    Liu, Xiang
    Poo, Yee-Suan
    Alves, Juliana C.
    Almeida, Roque P.
    Mostafavi, Helen
    Tang, Patrick Chun Hean
    Bucala, Richard
    Teixeira, Mauro M.
    Taylor, Adam
    Zaid, Ali
    Mahalingam, Suresh
    MBIO, 2022, 13 (02):
  • [6] Chikungunya Virus-Associated Disease
    C. Hua
    B. Combe
    Current Rheumatology Reports, 2017, 19
  • [7] Chikungunya Virus-Associated Disease
    Hua, C.
    Combe, B.
    CURRENT RHEUMATOLOGY REPORTS, 2017, 19 (11)
  • [8] γδ T Cells Play a Protective Role in Chikungunya Virus-Induced Disease
    Long, Kristin M.
    Ferris, Martin T.
    Whitmore, Alan C.
    Montgomery, Stephanie A.
    Thurlow, Lance R.
    McGee, Charles E.
    Rodriguez, Carlos A.
    Lim, Jean K.
    Heise, Mark T.
    JOURNAL OF VIROLOGY, 2016, 90 (01) : 433 - 443
  • [9] Chikungunya Disease and Chloroquine Treatment
    Delogu, Ilenia
    de lamballerie, Xavier
    JOURNAL OF MEDICAL VIROLOGY, 2011, 83 (06) : 1058 - 1059
  • [10] Expression of the capsid protein of Chikungunya virus in a baculovirus for serodiagnosis of Chikungunya disease
    Cho, Byungki
    Kim, Jungho
    Cho, Jang-Eun
    Jeon, Bo-Young
    Park, Sun
    JOURNAL OF VIROLOGICAL METHODS, 2008, 154 (1-2) : 154 - 159