TACS (targacept active conformation search): A new method for predicting the conformation of a ligand bound to its protein target.

被引：0
|
作者：
Klucik, J [1 ]
Clauset, AJ [1 ]
Hammond, PS [1 ]
Harris, R [1 ]
Caldwell, WS [1 ]
Schmitt, JD [1 ]
机构：
[1] Targacept Inc, Mol Design Grp, Winston Salem, NC 27101 USA
来源：
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2002年 / 224卷
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
188-COMP
引用
收藏
页码：U497 / U497
页数：1
相关论文
共 9 条
  • [1] Targacept active conformation search: A new method for predicting the conformation of a ligand bound to its protein target
    Klucik, J
    Xiao, YD
    Hammond, PS
    Harris, R
    Schmitt, JD
    JOURNAL OF MEDICINAL CHEMISTRY, 2004, 47 (27) : 6831 - 6839
  • [2] Conformation of a peptide ligand bound to its G-protein coupled receptor
    Hiroshi Inooka
    Tetsuya Ohtaki
    Osamu Kitahara
    Takahisa Ikegami
    Satoshi Endo
    Chieko Kitada
    Kazuhiro Ogi
    Haruo Onda
    Masahiko Fujino
    Masahiro Shirakawa
    Nature Structural Biology, 2001, 8 : 161 - 165
  • [3] Conformation of a peptide ligand bound to its G-protein coupled receptor
    Inooka, H
    Ohtaki, T
    Kitahara, O
    Ikegami, T
    Endo, S
    Kitada, C
    Ogi, K
    Onda, H
    Fujino, M
    Shirakawa, M
    NATURE STRUCTURAL BIOLOGY, 2001, 8 (02) : 161 - 165
  • [4] A method of active conformation search based on active and inactive analogues and its application to allylamine antimycotics
    Wannian Zhang
    Haitao Ji
    Youjun Zhou
    Jie Zhu
    Ju Zhu
    Jiaguo Lü
    Science in China Series C: Life Sciences, 1999, 42 : 538 - 547
  • [5] A method of active conformation search based on active and inactive analogues and its application to allylamine antimycotics
    Zhang, WN
    Ji, HT
    Zhou, YJ
    Zhu, J
    Zhu, J
    Lü, JG
    SCIENCE IN CHINA SERIES C-LIFE SCIENCES, 1999, 42 (05): : 538 - 547
  • [6] A method of active conformation search based on active and inactive analogues, and its application to allylamine antimycotics
    张万年
    季海涛
    周有骏
    朱杰
    朱驹
    吕加国
    Science in China(Series C:Life Sciences), 1999, (05) : 538 - 547
  • [7] A general method for predicting the bound conformation and free energy of formation of protein/carbohydrate complexes.
    Laederach, A
    Reilly, PJ
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2003, 225 : U256 - U256
  • [8] THE ESCHERICHIA-COLI DNAK CHAPERONE, THE 70-KDA HEAT-SHOCK PROTEIN EUKARYOTIC EQUIVALENT, CHANGES CONFORMATION UPON ATP HYDROLYSIS, THUS TRIGGERING ITS DISSOCIATION FROM A BOUND TARGET PROTEIN
    LIBEREK, K
    SKOWYRA, D
    ZYLICZ, M
    JOHNSON, C
    GEORGOPOULOS, C
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1991, 266 (22) : 14491 - 14496
  • [9] NMR DISTANCE CONSTRAINT ANALYSIS FOR THE AGLYCON OF ARIDICIN A BOUND TO AC-LYS(AC)-D-ALA-D-ALA - A NEW METHOD FOR PREDICTING WELL-DEFINED AND VARIABLE REGIONS OF MOLECULAR-CONFORMATION DEFINED BY DISTANCE CONSTRAINTS
    HEMPEL, JC
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1989, 111 (02) : 491 - 495
1