Efficiency of visual information processing in children at-risk for dyslexia: Habituation of single-trial ERPs

To investigate underlying learning mechanisms in relation to the development of dyslexia, event-related potentials to visual standards were recorded in five-year-old pre-reading children at-risk for familial dyslexia (n = 24) and their controls (n = 14). At the end of second grade the children aged 8 years were regrouped into three groups according to literacy level and risk factor. Single-trial analyses revealed N1 habituation in the normal-reading controls, but not in the normal-reading at-risks, and a N1 amplitude increase in the group of poor-reading at-risks and poor-reading controls. No P3 habituation was found in either group. The normal-reading at-risk group exhibited the longest N1 and P3 latencies, possibly compensating for their reduced neuronal activity during initial information extraction. In contrast, the poor-reading group only showed prolonged P3, and their increase in (initial small) NI amplitude together with normal N1 latencies, suggests inefficient processing in an early time window, which might explain automatisation difficulties in dyslexic readers. (c) 2006 Elsevier Inc. All rights reserved.