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- [1] Phase I Dose-Escalation and -Expansion Study of the BRAF Inhibitor Encorafenib (LGX818) in Metastatic BRAF-Mutant MelanomaCLINICAL CANCER RESEARCH, 2017, 23 (18) : 5339 - 5348Delord, Jean-Pierre论文数: 0 引用数: 0 h-index: 0机构: Inst Univ Canc, Toulouse, France Inst Univ Canc, Toulouse, FranceRobert, Caroline论文数: 0 引用数: 0 h-index: 0机构: Gustave Roussy & Paris Sud Univ, Villejuif, France Inst Univ Canc, Toulouse, FranceNyakas, Marta论文数: 0 引用数: 0 h-index: 0机构: Oslo Univ Hosp, Oslo, Norway Inst Univ Canc, Toulouse, FranceMcArthur, Grant A.论文数: 0 引用数: 0 h-index: 0机构: Peter MacCallum Canc Ctr, Melbourne, Vic, Australia Univ Melbourne, Melbourne, Vic, Australia Inst Univ Canc, Toulouse, FranceKudchakar, Ragini论文数: 0 引用数: 0 h-index: 0机构: Emory Univ, Winship Canc Inst, Atlanta, GA 30322 USA Inst Univ Canc, Toulouse, FranceMahipal, Amit论文数: 0 引用数: 0 h-index: 0机构: Lee Moffitt Canc Ctr & Res Inst, Tampa, FL USA Inst Univ Canc, Toulouse, FranceYamada, Yasuhide论文数: 0 引用数: 0 h-index: 0机构: Natl Canc Ctr, Tokyo, Japan Inst Univ Canc, Toulouse, FranceSullivan, Ryan论文数: 0 引用数: 0 h-index: 0机构: Massachusetts Gen Hosp, Boston, MA 02114 USA Inst Univ Canc, Toulouse, FranceArance, Ana论文数: 0 引用数: 0 h-index: 0机构: Hosp Clin Barcelona, Dept Med Oncol & Translat Genom & Targeted Therap, Barcelona, Spain Inst Univ Canc, Toulouse, FranceKefford, Richard F.论文数: 0 引用数: 0 h-index: 0机构: Univ Sydney, Melanoma Inst Australia, Crown Princess Mary Canc Ctr, Westmead Hosp, Sydney, NSW, Australia Macquarie Univ, Sydney, NSW, Australia Inst Univ Canc, Toulouse, FranceCarlino, Matteo S.论文数: 0 引用数: 0 h-index: 0机构: Univ Sydney, Melanoma Inst Australia, Crown Princess Mary Canc Ctr, Westmead Hosp, Sydney, NSW, Australia Inst Univ Canc, Toulouse, FranceHidalgo, Manuel论文数: 0 引用数: 0 h-index: 0机构: Spanish Natl Canc Res Ctr CNIO, Madrid, Spain Ctr Integral Oncol Clara Campal, Madrid, Spain Inst Univ Canc, Toulouse, FranceGomez-Roca, Carlos论文数: 0 引用数: 0 h-index: 0机构: Inst Univ Canc, Toulouse, France Inst Univ Canc, Toulouse, FranceMichel, Daniela论文数: 0 引用数: 0 h-index: 0机构: Novartis Pharma AG, Basel, Switzerland Inst Univ Canc, Toulouse, FranceSeroutou, Abdelkader论文数: 0 引用数: 0 h-index: 0机构: Novartis Pharma AG, Basel, Switzerland Inst Univ Canc, Toulouse, FranceAslanis, Vassilios论文数: 0 引用数: 0 h-index: 0机构: Novartis Pharma AG, Basel, Switzerland Inst Univ Canc, Toulouse, FranceCaponigro, Giordano论文数: 0 引用数: 0 h-index: 0机构: Novartis Inst Biomed Res, Cambridge, MA USA Inst Univ Canc, Toulouse, FranceStuart, Darrin D.论文数: 0 引用数: 0 h-index: 0机构: Novartis Inst Biomed Res, Cambridge, MA USA Inst Univ Canc, Toulouse, FranceMoutouh-de Parseval, Laure论文数: 0 引用数: 0 h-index: 0机构: Novartis Pharma AG, Basel, Switzerland Inst Univ Canc, Toulouse, FranceDemuth, Tim论文数: 0 引用数: 0 h-index: 0机构: Novartis Pharma AG, Basel, Switzerland Inst Univ Canc, Toulouse, FranceDummer, Reinhard论文数: 0 引用数: 0 h-index: 0机构: Univ Hosp Zurich, Zurich, Switzerland Inst Univ Canc, Toulouse, France
- [2] Preliminary results from a phase Ib/II, open-label, dose-escalation study of the oral BRAF inhibitor LGX818 in combination with the oral MEK1/2 inhibitor MEK162 in BRAF V600-dependent advanced solid tumorsJOURNAL OF CLINICAL ONCOLOGY, 2013, 31 (15)Kefford, Richard论文数: 0 引用数: 0 h-index: 0机构: Univ Sydney, Westmead Inst Canc Res, Melanoma Inst Australia, Sydney, NSW 2006, AustraliaMiller, Wilson H.论文数: 0 引用数: 0 h-index: 0机构: Univ Sydney, Westmead Inst Canc Res, Melanoma Inst Australia, Sydney, NSW 2006, AustraliaTan, Daniel Shao-Weng论文数: 0 引用数: 0 h-index: 0机构: Univ Sydney, Westmead Inst Canc Res, Melanoma Inst Australia, Sydney, NSW 2006, AustraliaSullivan, Ryan J.论文数: 0 引用数: 0 h-index: 0机构: Univ Sydney, Westmead Inst Canc Res, Melanoma Inst Australia, Sydney, NSW 2006, AustraliaLong, Georgina论文数: 0 引用数: 0 h-index: 0机构: Univ Sydney, Westmead Inst Canc Res, Melanoma Inst Australia, Sydney, NSW 2006, AustraliaDienstmann, Rodrigo论文数: 0 引用数: 0 h-index: 0机构: Univ Sydney, Westmead Inst Canc Res, Melanoma Inst Australia, Sydney, NSW 2006, AustraliaTai, Wai Meng David论文数: 0 引用数: 0 h-index: 0机构: Univ Sydney, Westmead Inst Canc Res, Melanoma Inst Australia, Sydney, NSW 2006, AustraliaFlaherty, Keith论文数: 0 引用数: 0 h-index: 0机构: Univ Sydney, Westmead Inst Canc Res, Melanoma Inst Australia, Sydney, NSW 2006, AustraliaStutvoet, Simone论文数: 0 引用数: 0 h-index: 0机构: Univ Sydney, Westmead Inst Canc Res, Melanoma Inst Australia, Sydney, NSW 2006, AustraliaSchumacher, Karl Maria论文数: 0 引用数: 0 h-index: 0机构: Univ Sydney, Westmead Inst Canc Res, Melanoma Inst Australia, Sydney, NSW 2006, AustraliaWandel, Simon论文数: 0 引用数: 0 h-index: 0机构: Univ Sydney, Westmead Inst Canc Res, Melanoma Inst Australia, Sydney, NSW 2006, AustraliaDe Parseval, Laure A.论文数: 0 引用数: 0 h-index: 0机构: Univ Sydney, Westmead Inst Canc Res, Melanoma Inst Australia, Sydney, NSW 2006, AustraliaTabernero, Josep论文数: 0 引用数: 0 h-index: 0机构: Univ Sydney, Westmead Inst Canc Res, Melanoma Inst Australia, Sydney, NSW 2006, Australia
- [3] Phase Ib/II, open-label, dose-escalation study of LGX818, an oral selective BRAF inhibitor, in combination with MEK162, an oral MEK1/2 inhibitor, in patients with BRAF V600-dependent advanced solid tumors: preliminary resultsJournal of Translational Medicine, 12 (Suppl 1)Richard Kefford论文数: 0 引用数: 0 h-index: 0机构: The University of Sydney,Melanoma Institute Australia, Westmead Institute for Cancer Research and Westmead HospitalRyan J Sullivan论文数: 0 引用数: 0 h-index: 0机构: The University of Sydney,Melanoma Institute Australia, Westmead Institute for Cancer Research and Westmead HospitalWilson H Miller论文数: 0 引用数: 0 h-index: 0机构: The University of Sydney,Melanoma Institute Australia, Westmead Institute for Cancer Research and Westmead HospitalElena M Elez论文数: 0 引用数: 0 h-index: 0机构: The University of Sydney,Melanoma Institute Australia, Westmead Institute for Cancer Research and Westmead HospitalDaniel Tan论文数: 0 引用数: 0 h-index: 0机构: The University of Sydney,Melanoma Institute Australia, Westmead Institute for Cancer Research and Westmead HospitalKevin B Kim论文数: 0 引用数: 0 h-index: 0机构: The University of Sydney,Melanoma Institute Australia, Westmead Institute for Cancer Research and Westmead HospitalGeorgina V Long论文数: 0 引用数: 0 h-index: 0机构: The University of Sydney,Melanoma Institute Australia, Westmead Institute for Cancer Research and Westmead HospitalKeith T Flaherty论文数: 0 引用数: 0 h-index: 0机构: The University of Sydney,Melanoma Institute Australia, Westmead Institute for Cancer Research and Westmead HospitalDavid Tai论文数: 0 引用数: 0 h-index: 0机构: The University of Sydney,Melanoma Institute Australia, Westmead Institute for Cancer Research and Westmead HospitalSimone Stutvoet论文数: 0 引用数: 0 h-index: 0机构: The University of Sydney,Melanoma Institute Australia, Westmead Institute for Cancer Research and Westmead HospitalHeiko Maacke论文数: 0 引用数: 0 h-index: 0机构: The University of Sydney,Melanoma Institute Australia, Westmead Institute for Cancer Research and Westmead HospitalMatt Whiley论文数: 0 引用数: 0 h-index: 0机构: The University of Sydney,Melanoma Institute Australia, Westmead Institute for Cancer Research and Westmead HospitalLaure Moutouh-de Parseval论文数: 0 引用数: 0 h-index: 0机构: The University of Sydney,Melanoma Institute Australia, Westmead Institute for Cancer Research and Westmead HospitalJosep Tabernero论文数: 0 引用数: 0 h-index: 0机构: The University of Sydney,Melanoma Institute Australia, Westmead Institute for Cancer Research and Westmead Hospital
- [4] PHASE IB/II STUDY OF LEE011 (CDK4/6 INHIBITOR) AND LGX818 (BRAF INHIBITOR) IN BRAF-MUTANT MELANOMAANNALS OF ONCOLOGY, 2014, 25Taylor, M.论文数: 0 引用数: 0 h-index: 0机构: Oregon Hlth & Sci Univ, Knight Canc Inst, Div Hematol & Med Oncol, Portland, OR 97201 USA Oregon Hlth & Sci Univ, Knight Canc Inst, Div Hematol & Med Oncol, Portland, OR 97201 USASosman, J.论文数: 0 引用数: 0 h-index: 0机构: Vanderbilt Ingram Canc Ctr, Dept Med, Nashville, TN USA Oregon Hlth & Sci Univ, Knight Canc Inst, Div Hematol & Med Oncol, Portland, OR 97201 USAGonzalez, R.论文数: 0 引用数: 0 h-index: 0机构: Univ Colorado, Ctr Canc, Div Med Oncol, Aurora, CO USA Oregon Hlth & Sci Univ, Knight Canc Inst, Div Hematol & Med Oncol, Portland, OR 97201 USACarlino, M. S.论文数: 0 引用数: 0 h-index: 0机构: Westmead Hosp, Dept Med Oncol, Sydney, NSW, Australia Blacktown Hosp, Dept Med Oncol, Sydney, NSW, Australia Oregon Hlth & Sci Univ, Knight Canc Inst, Div Hematol & Med Oncol, Portland, OR 97201 USAKittaneh, M.论文数: 0 引用数: 0 h-index: 0机构: Wayne State Univ, Barbara Ann Karmanos Canc Inst, Dept Oncol, Detroit, MI USA Oregon Hlth & Sci Univ, Knight Canc Inst, Div Hematol & Med Oncol, Portland, OR 97201 USALolkema, M. P.论文数: 0 引用数: 0 h-index: 0机构: Univ Med Ctr Utrecht, Dept Med Oncol, Utrecht, Netherlands Oregon Hlth & Sci Univ, Knight Canc Inst, Div Hematol & Med Oncol, Portland, OR 97201 USAMiller, W.论文数: 0 引用数: 0 h-index: 0机构: McGill Univ, Dept Oncol, Montreal, PQ, Canada Oregon Hlth & Sci Univ, Knight Canc Inst, Div Hematol & Med Oncol, Portland, OR 97201 USAMarino, A.论文数: 0 引用数: 0 h-index: 0机构: Novartis Inst BioMed Res, Cambridge, MA USA Oregon Hlth & Sci Univ, Knight Canc Inst, Div Hematol & Med Oncol, Portland, OR 97201 USAZhang, V.论文数: 0 引用数: 0 h-index: 0机构: Novartis Inst BioMed Res, Cambridge, MA USA Oregon Hlth & Sci Univ, Knight Canc Inst, Div Hematol & Med Oncol, Portland, OR 97201 USABhansali, S. G.论文数: 0 引用数: 0 h-index: 0机构: Novartis Pharmaceut, Clincal Pharmacol, E Hanover, NJ USA Oregon Hlth & Sci Univ, Knight Canc Inst, Div Hematol & Med Oncol, Portland, OR 97201 USAParasuraman, S.论文数: 0 引用数: 0 h-index: 0机构: Novartis Inst BioMed Res, Cambridge, MA USA Oregon Hlth & Sci Univ, Knight Canc Inst, Div Hematol & Med Oncol, Portland, OR 97201 USAPostow, M. A.论文数: 0 引用数: 0 h-index: 0机构: Mem Sloan Kettering Canc Ctr, Dept Med, New York, NY 10021 USA Oregon Hlth & Sci Univ, Knight Canc Inst, Div Hematol & Med Oncol, Portland, OR 97201 USA
- [5] Final biomarker analysis of the phase I study of the selective BRAF V600 inhibitor encorafenib (LGX818) combined with cetuximab with or without the α-specific PI3K inhibitor alpelisib (BYL719) in patients with advanced BRAF-mutant colorectal cancerCANCER RESEARCH, 2015, 75Schellens, Jan H. M.论文数: 0 引用数: 0 h-index: 0机构: Netherlands Canc Inst, Amsterdam, Netherlands Netherlands Canc Inst, Amsterdam, Netherlandsvan Geel, Robin论文数: 0 引用数: 0 h-index: 0机构: Netherlands Canc Inst, Amsterdam, Netherlands Netherlands Canc Inst, Amsterdam, NetherlandsBendell, Johanna C.论文数: 0 引用数: 0 h-index: 0机构: Sarah Cannon Res Inst, Nashville, TN USA Netherlands Canc Inst, Amsterdam, NetherlandsSpreafico, Anna论文数: 0 引用数: 0 h-index: 0机构: Princess Margaret Canc Ctr, Toronto, ON, Canada Netherlands Canc Inst, Amsterdam, NetherlandsSchuler, Martin论文数: 0 引用数: 0 h-index: 0机构: Univ Hosp Essen, West German Canc Ctr, Essen, Germany Netherlands Canc Inst, Amsterdam, NetherlandsYoshino, Takayuki论文数: 0 引用数: 0 h-index: 0机构: Natl Canc Ctr Hosp East, Chiba, Japan Netherlands Canc Inst, Amsterdam, NetherlandsDelord, Jean-Pierre论文数: 0 引用数: 0 h-index: 0机构: Inst Claudius Regaud, Toulouse, France Netherlands Canc Inst, Amsterdam, NetherlandsYamada, Yasuhide论文数: 0 引用数: 0 h-index: 0机构: Natl Canc Ctr, Tokyo, Japan Netherlands Canc Inst, Amsterdam, NetherlandsLolkema, Martijn P.论文数: 0 引用数: 0 h-index: 0机构: Univ Med Ctr Utrecht, Utrecht, Netherlands Netherlands Canc Inst, Amsterdam, NetherlandsFaris, Jason E.论文数: 0 引用数: 0 h-index: 0机构: Massachusetts Gen Hosp, Boston, MA 02114 USA Netherlands Canc Inst, Amsterdam, NetherlandsEskens, Ferry A. L. M.论文数: 0 引用数: 0 h-index: 0机构: Erasmus MC Canc Inst, Rotterdam, Netherlands Netherlands Canc Inst, Amsterdam, NetherlandsSharma, Sunil论文数: 0 引用数: 0 h-index: 0机构: Univ Utah, Huntsman Canc Inst, Salt Lake City, UT USA Netherlands Canc Inst, Amsterdam, NetherlandsYaeqer, Rona论文数: 0 引用数: 0 h-index: 0机构: Mem Sloan Kettering Canc Ctr, New York, NY 10021 USA Netherlands Canc Inst, Amsterdam, NetherlandsLenz, Heinz-Josef论文数: 0 引用数: 0 h-index: 0机构: Univ So Calif, Keck Sch Med, Los Angeles, CA 90033 USA Netherlands Canc Inst, Amsterdam, NetherlandsWainberg, Zev A.论文数: 0 引用数: 0 h-index: 0机构: Univ Calif Los Angeles, Med Ctr, Santa Monica, CA USA Netherlands Canc Inst, Amsterdam, NetherlandsAvsar, Emin论文数: 0 引用数: 0 h-index: 0机构: Novartis Pharmaceut, E Hanover, NJ USA Netherlands Canc Inst, Amsterdam, NetherlandsChatterjee, Arkendu论文数: 0 引用数: 0 h-index: 0机构: Novartis Pharmaceut, E Hanover, NJ USA Netherlands Canc Inst, Amsterdam, NetherlandsJaeger, Savina论文数: 0 引用数: 0 h-index: 0机构: Novartis Inst Biomed Res, Cambridge, MA USA Netherlands Canc Inst, Amsterdam, NetherlandsDemuth, Tim论文数: 0 引用数: 0 h-index: 0机构: Novartis Pharma AG, Basel, Switzerland Netherlands Canc Inst, Amsterdam, NetherlandsTabemero, Josep论文数: 0 引用数: 0 h-index: 0机构: Vall Hebron Univ Hosp, Barcelona, Spain Netherlands Canc Inst, Amsterdam, Netherlands
- [6] Open-label, phase IIa study of dabrafenib plus trametinib in East Asian patients with advanced BRAF V600-mutant cutaneous melanomaEUROPEAN JOURNAL OF CANCER, 2020, 135 : 31 - 38Si, Lu论文数: 0 引用数: 0 h-index: 0机构: Peking Univ, Dept Kidney Canc & Melanoma, Key Lab Carcinogenesis & Translat Res, Minist Educ Beijing,Canc Hosp & Inst, Beijing, Peoples R China Peking Univ, Dept Kidney Canc & Melanoma, Key Lab Carcinogenesis & Translat Res, Minist Educ Beijing,Canc Hosp & Inst, Beijing, Peoples R ChinaZhang, Xiaoshi论文数: 0 引用数: 0 h-index: 0机构: Sun Yat Sen Univ, Canc Ctr, Guangzhou, Peoples R China Peking Univ, Dept Kidney Canc & Melanoma, Key Lab Carcinogenesis & Translat Res, Minist Educ Beijing,Canc Hosp & Inst, Beijing, Peoples R ChinaShin, Sang Joon论文数: 0 引用数: 0 h-index: 0机构: Yonsei Univ, Coll Med, Seoul, South Korea Peking Univ, Dept Kidney Canc & Melanoma, Key Lab Carcinogenesis & Translat Res, Minist Educ Beijing,Canc Hosp & Inst, Beijing, Peoples R ChinaFan, Yun论文数: 0 引用数: 0 h-index: 0机构: Zhejiang Canc Hosp, Hangzhou, Peoples R China Peking Univ, Dept Kidney Canc & Melanoma, Key Lab Carcinogenesis & Translat Res, Minist Educ Beijing,Canc Hosp & Inst, Beijing, Peoples R ChinaLin, Chia-Chi论文数: 0 引用数: 0 h-index: 0机构: Natl Taiwan Univ Hosp, Dept Oncol, Taipei, Taiwan Peking Univ, Dept Kidney Canc & Melanoma, Key Lab Carcinogenesis & Translat Res, Minist Educ Beijing,Canc Hosp & Inst, Beijing, Peoples R ChinaKim, Tae Min论文数: 0 引用数: 0 h-index: 0机构: Seoul Natl Univ Hosp, Dept Internal Med, Seoul, South Korea Peking Univ, Dept Kidney Canc & Melanoma, Key Lab Carcinogenesis & Translat Res, Minist Educ Beijing,Canc Hosp & Inst, Beijing, Peoples R China论文数: 引用数: h-index:机构:Maneechavakajorn, Jedzada论文数: 0 引用数: 0 h-index: 0机构: Rajavithi Hosp, Bangkok, Thailand Peking Univ, Dept Kidney Canc & Melanoma, Key Lab Carcinogenesis & Translat Res, Minist Educ Beijing,Canc Hosp & Inst, Beijing, Peoples R ChinaWong, Chi Sing论文数: 0 引用数: 0 h-index: 0机构: Tuen Mun Hosp, Dept Clin Oncol, Tuen Mun, Hong Kong, Peoples R China Peking Univ, Dept Kidney Canc & Melanoma, Key Lab Carcinogenesis & Translat Res, Minist Educ Beijing,Canc Hosp & Inst, Beijing, Peoples R ChinaIlankumaran, Palanichamy论文数: 0 引用数: 0 h-index: 0机构: Novartis Pharmaceut, E Hanover, NJ USA Peking Univ, Dept Kidney Canc & Melanoma, Key Lab Carcinogenesis & Translat Res, Minist Educ Beijing,Canc Hosp & Inst, Beijing, Peoples R ChinaLee, Dung-Yang论文数: 0 引用数: 0 h-index: 0机构: Novartis Pharmaceut, E Hanover, NJ USA Univ Texas Houston, Sch Hlth Sci Ctr, Houston, TX USA Peking Univ, Dept Kidney Canc & Melanoma, Key Lab Carcinogenesis & Translat Res, Minist Educ Beijing,Canc Hosp & Inst, Beijing, Peoples R ChinaGasal, Eduard论文数: 0 引用数: 0 h-index: 0机构: Novartis Pharmaceut, E Hanover, NJ USA Peking Univ, Dept Kidney Canc & Melanoma, Key Lab Carcinogenesis & Translat Res, Minist Educ Beijing,Canc Hosp & Inst, Beijing, Peoples R ChinaLi, Haifu论文数: 0 引用数: 0 h-index: 0机构: China Novartis Inst BioMed Res, Beijing, Peoples R China Peking Univ, Dept Kidney Canc & Melanoma, Key Lab Carcinogenesis & Translat Res, Minist Educ Beijing,Canc Hosp & Inst, Beijing, Peoples R ChinaGuo, Jun论文数: 0 引用数: 0 h-index: 0机构: Peking Univ, Dept Urol & Melanoma, Canc Hosp & Inst, Beijing, Peoples R China Peking Univ, Dept Kidney Canc & Melanoma, Key Lab Carcinogenesis & Translat Res, Minist Educ Beijing,Canc Hosp & Inst, Beijing, Peoples R China
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