Synthesis of Mesoionic Isoquinolines by Rhodium(III)-Catalyzed C-H Activation

被引：18

作者：

Zhang, Wei ^{[1
]}

Wang, Cheng-Qi ^{[1
]}

Lin, Hui ^{[1
]}

Dong, Lin ^{[1
]}

Xu, Yan-Jun ^{[2
]}

机构：

[1] Sichuan Univ, West China Sch Pharm, Minist Educ, Key Lab Drug Targeting & Drug Delivery Syst, Chengdu 610041, Peoples R China

[2] Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Urumqi 830011, Peoples R China

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2016年 / 22卷 / 03期

关键词：

annulation; benzaldimines; copper; homogeneous catalysis; isoquinolines; rhodium; NICKEL-CATALYZED ANNULATION; BOND ACTIVATION; INTERNAL ALKYNES; CYCLOADDITION REACTIONS; RHODIUM CATALYSIS; INNER SALTS; N-AMINIDES; DERIVATIVES; MECHANISM; FUNCTIONALIZATION;

D O I：

10.1002/chem.201504245

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Hydroxyl-substituted benzaldimines underwent a Rh-III-catalyzed C-H activation and annulation with alkynes to provide novel mesoionic isoquinoline derivatives in moderate to excellent yields using oxygen as an internal anion source. This simple and efficient approach has a broad substrate scope.

引用

页码：907 / 910

页数：4

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