SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF NEW 1,3-THIAZOLYLQUINAZOLIN-4-(3H)-ONES

被引:0
|
作者
Patel, N. B. [1 ]
Patel, J. N. [1 ]
机构
[1] Veer Narmad S Gujarat Univ, Dept Chem, Surat 395007, India
关键词
BIOLOGICAL EVALUATION; DERIVATIVES; ANTIBACTERIAL; AGENTS;
D O I
暂无
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Synthesis of 2-[2-(2,6-dichlorophenyl) amino] phenylmethyl-3-[4-substitutedanilino1,3-thiazol-2-yl]-6-iodoquinazolin-4-(3H) ones Va-o from 2-[(2,6-dichlorophenyl) amino]phenyl acetic acid I, via nucleophilic interaction of 2-[2-(2,6-dichlorophenyl) amino] phenylmethyl-6-iodo-3, 1-benzoxazin-4-(3H) ones III with thiourea nucleophile has been achieved. The final compounds have been characterized by analytical and spectral data (IR and H-1 NMR) and screened for their antimicrobial activity.
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页码:247 / 250
页数:4
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