Synthesis of Sterically Protected Xanthene Dyes with Bulky Groups at C-3′ and C-7′

被引：28

作者：

Lei, Zuhai ^{[2
]}

Li, Xinran ^{[2
]}

Li, Yi ^{[2
]}

Luo, Xiao ^{[2
]}

Zhou, Miaomiao ^{[2
]}

Yang, Youjun ^{[1
,2
]}

机构：

[1] E China Univ Sci & Technol, State Key Lab Bioreactor Engn, Sch Pharm, Shanghai 200237, Peoples R China

[2] E China Univ Sci & Technol, Shanghai Key Lab Chem Biol, Sch Pharm, Shanghai 200237, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2015年 / 80卷 / 22期

基金：

中国国家自然科学基金;

关键词：

SPECTROSCOPIC PROPERTIES; RHODAMINE-B; FLUORESCENT; ROTAXANES;

D O I：

10.1021/acs.joc.5b01746

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Substitution of-the xanthene scaffold,with-bulky groups at C-3' and C-7' is expected to protect the electrophilic central methine, carbon against nucleophilic attack. and inhibit, stacking. However, such,structures are not readily prepared via traditional xanthene syntheses. We have devised an alternative and :convenient synthesis to enable facile preparation of this subset of xanthene dyes Under mild conditions and in good yields.

引用

页码：11538 / 11543

页数：6

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