THE UNFOLDED PROTEIN RESPONSE OF IPSC-DERIVED MOTOR NEURONS IN MND

被引:0
|
作者
Gane, Angus Buchanan [1 ,2 ]
Selvaraj, Bhuvaneish Thangarai [2 ]
Chandran, Siddharthan [2 ]
机构
[1] Univ Edinburgh, Edinburgh, Midlothian, Scotland
[2] Scottish Ctr Regenerat Med, Edinburgh, Midlothian, Scotland
关键词
D O I
10.1136/jnnp-2017-ABN.195
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
PO172
引用
收藏
页码:A56 / A57
页数:2
相关论文
共 50 条
  • [1] Modeling Protein Aggregation and the Heat Shock Response in ALS iPSC-Derived Motor Neurons
    Seminary, Emily R.
    Sison, Samantha L.
    Ebert, Allison D.
    [J]. FRONTIERS IN NEUROSCIENCE, 2018, 12
  • [2] Modeling Protein Aggregation and the Heat Shock Response in ALS iPSC-derived Motor Neurons.
    Seminary, E. R.
    Sison, S. L.
    Ebert, A. D.
    [J]. MOLECULAR BIOLOGY OF THE CELL, 2017, 28
  • [3] Alpha-synuclein induces the unfolded protein response in Parkinson's disease SNCA triplication iPSC-derived neurons
    Heman-Ackah, Sabrina M.
    Manzano, Raquel
    Hoozemans, Jeroen J. M.
    Scheper, Wiep
    Flynn, Rowan
    Haerty, Wilfried
    Cowley, Sally A.
    Bassett, Andrew R.
    Wood, Matthew J. A.
    [J]. HUMAN MOLECULAR GENETICS, 2017, 26 (22) : 4441 - 4450
  • [4] Gene editing improves endoplasmic reticulum-mitochondrial contacts and unfolded protein response in Friedreich's ataxia iPSC-derived neurons
    Mishra, Priyanka
    Sivakumar, Anusha
    Johnson, Avalon
    Pernaci, Carla
    Warden, Anna S.
    El-Hachem, Lilas Rony
    Hansen, Emily
    Badell-Grau, Rafael A.
    Khare, Veenita
    Ramirez, Gabriela
    Gillette, Sydney
    Solis, Angelyn B.
    Guo, Peng
    Coufal, Nicole
    Cherqui, Stephanie
    [J]. FRONTIERS IN PHARMACOLOGY, 2024, 15
  • [5] IPSC-derived motor neurons recapitulate disease signatures of axonal CMT
    Van Lent, Jonas
    Verstraelen, Peter
    Asselbergh, Bob
    Adriaenssens, Elias
    Mateiu, Ligia
    De Winter, Vicky
    Juneja, Manisha
    Van den Bosch, Ludo
    De Vos, Winnok
    Timmerman, Vincent
    [J]. JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM, 2021, 26 (03) : 348 - 348
  • [6] Microglia Influence Neurofilament Deposition in ALS iPSC-Derived Motor Neurons
    Allison, Reilly L.
    Adelman, Jacob W.
    Abrudan, Jenica
    Urrutia, Raul A.
    Zimmermann, Michael T.
    Mathison, Angela J.
    Ebert, Allison D.
    [J]. GENES, 2022, 13 (02)
  • [7] The temporal characterization of iPSC-derived neurons
    Rosa, F.
    Loeffler, H.
    Mueller, S.
    Elsen, G. E.
    Lerche, H.
    Maljevic, S.
    [J]. HUMAN GENE THERAPY, 2016, 27 (11) : A79 - A79
  • [8] Alpha-Synuclein Induces the Unfolded Protein Response in Parkinson's Disease Patient-Specific SNCA Triplication iPSC-Derived Neurons
    Heman-Ackah, Sabrina M.
    [J]. NEUROSURGERY, 2018, 65 : 138 - 139
  • [9] Serotype-specific sensitivity to Botulinum neurotoxins of iPSC-derived motor neurons
    Schenke, M.
    Schjeide, B. M.
    Pueschel, G. P.
    Seeger, B.
    [J]. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2021, 394 (SUPPL 1) : S4 - S4
  • [10] Ubiquitin proteasome system dysfunction in ALS patient IPSC-derived motor neurons
    Bax, M.
    Do-Ha, D.
    Yang, S.
    Blair, I.
    Yerbury, J.
    Ooi, L.
    [J]. JOURNAL OF NEUROCHEMISTRY, 2017, 142 : 214 - 214