End-of-life sedation: is there an alternative?

Purpose of review To evaluate the place and the usefulness of sedation in medical practice at the end of life. Recent findings Continuous sedation is an acknowledged medical practice for the management of refractory symptoms at the end of life. Guidelines and recommendations have been proposed in palliative care. Although considered as a good medical practice at the end of life, sedation is neither the only option nor the best. Summary This article presents the state-of-the-art (definitions, indications, and technical aspects) about continuous sedation, followed by an ethical reflection essentially based on the 'Principle of Double Effect', the impact on life expectancy, and the concept of 'natural death'.