Investigating the use of primary adult subventricular zone neural precursor cells for neuronal replacement therapies

被引:16
|
作者
Lim, DA
Flames, N
Collado, L
Herrera, DG
机构
[1] Cornell Univ, Dept Psychiat, Weill Med Coll, New York, NY 10021 USA
[2] Univ Valencia, Dept Biol Celular, Valencia, Spain
关键词
graft; adult neurogenesis; neural precursors; brain repair; SVZ;
D O I
10.1016/S0361-9230(01)00768-7
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
With the relatively recent discovery that neurogenesis persists throughout life in restricted regions of the adult mammalian brain, including those of human beings, there has been great interest in the use of adult-derived neural stem cells for neuronal replacement. There are many great hurdles that must be overcome in order for such replacement strategies to succeed. In this review, we outline some of these hurdles and discuss recent experiments that investigate the potential of using neural precursor cells found in the subventricular zone of the adult brain for brain repair. (C) 2002 Elsevier Science Inc.
引用
收藏
页码:759 / 764
页数:6
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