Identifying targets for osteoporosis via whole exome sequencing and CRISPR-Cas9

被引:0
|
作者
Zhou, S. [1 ]
Laurent, L. [1 ]
Kemp, J. P. [2 ]
Forgetta, V. [1 ]
Morris, J. [3 ]
Pramatarova, A. [4 ,5 ]
Croucher, P. I. [6 ]
Bassett, J. [7 ]
Goltzman, D. [8 ]
Evans, D. M. [2 ]
Richards, J. [1 ]
机构
[1] McGill Univ, Jewish Gen Hosp, Montreal, PQ, Canada
[2] Univ Queensland, Translat Res Inst, Diamantina Inst, Brisbane, Qld, Australia
[3] New York Genome Ctr, New York, NY USA
[4] McGill Univ, Montreal, PQ, Canada
[5] Genome Quebec Innovat Ctr, Montreal, PQ, Canada
[6] Garvan Inst Med Res, Sydney, NSW, Australia
[7] Imperial Coll London, Dept Med, Mol Endocrinol Lab, London, England
[8] McGill Univ, Res Inst, Ctr Hlth, Montreal, PQ, Canada
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
C29.6
引用
收藏
页码:134 / 134
页数:1
相关论文
共 50 条
  • [1] Identifying Drug Targets via Whole Exome Sequencing and CRISPR-Cas9
    Zhou, Sirui
    Laurent, Laetitia
    Kemp, John
    Pramatarova, Albena
    Forgetta, Vincenzo
    Morris, John
    Croucher, Peter
    Williams, Graham
    Bassett, Duncan
    Goltzman, David
    Lotta, Luca
    Evans, David
    Richards, Brent
    JOURNAL OF BONE AND MINERAL RESEARCH, 2020, 35 : 22 - 22
  • [2] Identification and Validation of Targets for Osteoporosis: Evidence from Whole exome Sequencing in 42,263 individuals, CRISPR-Cas9 and murine models
    Laurent, Laetitia
    Zhou, Sirui
    Forgetta, Vincenzo
    Richards, J. Brent
    Kemp, John P.
    Evans, David M.
    Pramatarova, Albena
    Croucher, Peter I.
    Williams, Graham R.
    Bassett, J. H. Duncan
    Goltzman, David
    JOURNAL OF BONE AND MINERAL RESEARCH, 2019, 34 : 28 - 28
  • [3] Identification of drug-specific resistance mechanisms in multiple myeloma by combining whole exome sequencing and CRISPR-Cas9 screens
    Bohl, S.
    Schmalbrock, L.
    Bauhuf, I
    Meyer, T.
    Dolnik, A.
    Blaette, T.
    Knoedler, S.
    Miller, D.
    Kull, M.
    Langer, C.
    Letai, A.
    Doehner, H.
    Heckl, D.
    Bullinger, L.
    Kroenke, J.
    ONCOLOGY RESEARCH AND TREATMENT, 2020, 43 (SUPPL 4) : 99 - 100
  • [4] identifying synthetic lethal targets in colon cancer using CRISPR-Cas9 and siRNA screens
    Russell, P.
    Walter, D.
    Yarker, J.
    Wiggins, C.
    Moore, J.
    EUROPEAN JOURNAL OF CANCER, 2016, 69 : S129 - S129
  • [5] Finding the Needle: Targeted Nanopore Sequencing and CRISPR-Cas9
    Loose, Matthew
    CRISPR JOURNAL, 2018, 1 (04): : 265 - 267
  • [6] Chromosome drives via CRISPR-Cas9 in yeast
    Hui Xu
    Mingzhe Han
    Shiyi Zhou
    Bing-Zhi Li
    Yi Wu
    Ying-Jin Yuan
    Nature Communications, 11
  • [7] Chromosome drives via CRISPR-Cas9 in yeast
    Xu, Hui
    Han, Mingzhe
    Zhou, Shiyi
    Li, Bing-Zhi
    Wu, Yi
    Yuan, Ying-Jin
    NATURE COMMUNICATIONS, 2020, 11 (01)
  • [8] Toward Whole-Transcriptome Editing with CRISPR-Cas9
    Heckl, Dirk
    Charpentier, Emmanuelle
    MOLECULAR CELL, 2015, 58 (04) : 560 - 562
  • [9] Scientists Journey Into Genomes Via CRISPR-Cas9
    Ricks, Delthia
    JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2015, 107 (11):
  • [10] CRISPR-Cas9 potential for identifying novel therapeutic targets in muscle-invasive bladder cancer
    Smith, Danielle J.
    Lunj, Sapna
    Adamson, Antony D.
    Nagarajan, Sankari
    Smith, Tim A. D.
    Reeves, Kimberley J.
    Hoskin, Peter J.
    Choudhury, Ananya
    NATURE REVIEWS UROLOGY, 2025, 22 (01) : 55 - 65