Tumor RIPK1 signaling mediates intrinsic and extrinsic mechanisms of resistance to immune checkpoint blockade therapy

被引：0
|
作者：
Cucolo, Lisa [1 ,2 ]
Qiu, Jingya [1 ,2 ]
Klapholz, Max [1 ,2 ]
Shi, Junwei [3 ]
Gilliland, Gary [4 ]
Jordan, Martha [5 ]
Minn, Andy [1 ,2 ,6 ]
机构：
[1] Univ Penn, Perelman Sch Med, Abramson Canc Ctr, Philadelphia, PA 19104 USA
[2] Univ Penn, Perelman Sch Med, Dept Radiat Oncol, Philadelphia, PA USA
[3] Univ Penn, Perelman Sch Med, Dept Canc Biol, Philadelphia, PA USA
[4] Univ Washington, Fred Hutchinson Canc Res Ctr, Seattle, WA 98195 USA
[5] Univ Penn, Perelman Sch Med Pathol & Lab Med, Philadelphia, PA 19104 USA
[6] Univ Penn, Parker Inst Canc Immunotherapy, Philadelphia, PA 19104 USA
来源：
JOURNAL OF IMMUNOLOGY | 2020年 / 204卷 / 01期
关键词：
D O I：
暂无
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
241.29
引用
收藏
页数：2
相关论文
共 50 条
  • [1] The interferon-stimulated gene RIPK1 regulates cancer cell intrinsic and extrinsic resistance to immune checkpoint blockade
    Cucolo, Lisa
    Chen, Qingzhou
    Qiu, Jingya
    Yu, Yongjun
    Klapholz, Max
    Budinich, Krista A.
    Zhang, Zhaojun
    Shao, Yue
    Brodsky, Igor E.
    Jordan, Martha S.
    Gilliland, D. Gary
    Zhang, Nancy R.
    Shi, Junwei
    Minn, Andy J.
    IMMUNITY, 2022, 55 (04) : 671 - +
  • [2] RIPK1 PROMOTES INTRINSIC AND EXTRINSIC RESISTANCE TO IMMUNOTHERAPY
    不详
    CANCER DISCOVERY, 2022, 12 (07) : 1607 - 1607
  • [3] Resistance Mechanisms to Immune-Checkpoint Blockade in Cancer: Tumor-Intrinsic and -Extrinsic Factors
    Pitt, Jonathan M.
    Vetizou, Marie
    Daillere, Romain
    Roberti, Maria Paula
    Yamazaki, Takahiro
    Routy, Bertrand
    Lepage, Patricia
    Boneca, Ivo Gomperts
    Chamaillard, Mathias
    Kroemer, Guido
    Zitvogel, Laurence
    IMMUNITY, 2016, 44 (06) : 1255 - 1269
  • [4] Loss of Tumor Intrinsic RIPK1, Antitumor Immune Responses, and the Efficacy of PD-1 Blockade
    Teng, F.
    Wang, P.
    Li, Y.
    Yuan, J.
    Yin, T.
    Shi, X.
    Xu, J.
    Liu, C.
    Yu, J.
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2024, 120 (02): : E403 - E403
  • [5] hMENA isoforms regulate cancer intrinsic type I IFN signaling and extrinsic mechanisms of resistance to immune checkpoint blockade in NSCLC
    Trono, Paola
    Tocci, Annalisa
    Palermo, Belinda
    Di Carlo, Anna
    D'Ambrosio, Lorenzo
    D'Andrea, Daniel
    Di Modugno, Francesca
    De Nicola, Francesca
    Goeman, Frauke
    Corleone, Giacomo
    Warren, Sarah
    Paolini, Francesca
    Panetta, Mariangela
    Sperduti, Isabella
    Baldari, Silvia
    Visca, Paolo
    Carpano, Silvia
    Cappuzzo, Federico
    Russo, Vincenzo
    Tripodo, Claudio
    Zucali, Paolo
    Gregorc, Vanesa
    Marchesi, Federica
    Nistico, Paola
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2023, 11 (08)
  • [6] Intrinsic Resistance of Solid Tumors to Immune Checkpoint Blockade Therapy
    Zhao, Xianda
    Subramanian, Subbaya
    CANCER RESEARCH, 2017, 77 (04) : 817 - 822
  • [7] Mechanisms of Resistance to Immune Checkpoint Blockade
    David Liu
    Russell W. Jenkins
    Ryan J. Sullivan
    American Journal of Clinical Dermatology, 2019, 20 : 41 - 54
  • [8] Mechanisms of Resistance to Immune Checkpoint Blockade
    Liu, David
    Jenkins, Russell W.
    Sullivan, Ryan J.
    AMERICAN JOURNAL OF CLINICAL DERMATOLOGY, 2019, 20 (01) : 41 - 54
  • [9] Mechanisms of tumor resistance to immune checkpoint blockade and combination strategies to overcome resistance
    Zhou, Xiaoting
    Ni, Yanghong
    Liang, Xiao
    Lin, Yi
    An, Biao
    He, Xiang
    Zhao, Xia
    FRONTIERS IN IMMUNOLOGY, 2022, 13
  • [10] Development of novel syngeneic tumor models with intrinsic or extrinsic resistance mechanisms to PD-1 blockade
    Wang, Xiaomin
    Zhang, Ziwei
    Liu, Longzhou
    Zhang, Xue
    Wang, Dong
    Xu, Nengwei
    Qiang, Xiangnan
    Gu, Qingyang
    Xiang, Jian
    Zhang, Zhixiang
    CANCER RESEARCH, 2024, 84 (06)
12345