IL-10 expressed by activated hepatic stellate cells (HSC) downregulates collagen gene and upregulates MMP-1 gene expression.

被引：0
|
作者：
Wang, SC
Ohata, M
Schrum, L
Rippe, RA
Tsukamoto, H
机构：
[1] UNIV SO CALIF,SCH MED,DIV GASTROINTESTINAL & LIVER DIS,LOS ANGELES,CA 90033
[2] VA OUTPATIENT CLIN,LOS ANGELES,CA
[3] UNIV N CAROLINA,DEPT MED,CHAPEL HILL,NC
来源：
HEPATOLOGY | 1997年 / 26卷 / 04期
关键词：
D O I：
暂无
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
引用
收藏
页码：825 / 825
页数：1
相关论文
共 50 条
  • [1] PPARΓ inhibits hepatic stellate cell collagen gene expression.
    Xiong, SG
    Miyahara, T
    Schrum, LW
    Yee, H
    Yavrom, SM
    She, H
    Willson, TM
    Tsukamoto, H
    [J]. HEPATOLOGY, 2000, 32 (04) : 185A - 185A
  • [2] IL-10 receptor and coreceptor expression in quiescent and activated hepatic stellate cells
    Mathurin, P
    Xiong, SG
    Kharbanda, KK
    Veal, N
    Miyahara, T
    Motomura, K
    Rippe, RA
    Bachem, MG
    Tsukamoto, H
    [J]. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 2002, 282 (06): : G981 - G990
  • [3] IL-10 expression by in vitro and in vivo activated hepatic stellate cells.
    Wang, SC
    Lin, M
    Ohata, M
    Pham, TV
    Tsukamoto, H
    [J]. HEPATOLOGY, 1996, 24 (04) : 1330 - 1330
  • [4] Homeobox gene Prx1 is expressed in activated hepatic stellate cells and transactivates collagen α1(I) promoter
    Jiang, Feng
    Stefanovic, Branko
    [J]. EXPERIMENTAL BIOLOGY AND MEDICINE, 2008, 233 (03) : 286 - 296
  • [5] Induction of usf binding activity in hepatic stellate cells is associated with increased alpha 1(I) collagen gene expression.
    Rippe, RA
    Kimball, JP
    Schrum, LW
    Breindl, M
    Brenner, DA
    [J]. HEPATOLOGY, 1996, 24 (04) : 276 - 276
  • [6] IL-10 receptor and co-receptor expression in quiescent and activated hepatic stellate cells.
    Mathurin, P
    Miyahara, T
    Motomura, K
    Tsukamoto, H
    [J]. HEPATOLOGY, 1999, 30 (04) : 488A - 488A
  • [7] IL-10 gene transfer downregulates allograft tracheal transplant induced IL-2 gene expression
    Boehler, A
    Chamberlain, D
    Bai, XH
    Xing, Z
    Liu, M
    Jordana, M
    Gauldie, J
    Slutsky, AS
    Keshavjee, S
    [J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1999, 159 (03) : A275 - A275
  • [8] An in vitro model with kryoconserved human activated hepatic stellate cells -: Reflecting heterogeneity of profibrotic and proinflammatory gene expression.
    Mühlbauer, M
    Thasler, W
    Weiss, T
    Schölmerich, J
    Hellerbrand, C
    [J]. HEPATOLOGY, 2002, 36 (04) : 487A - 487A
  • [9] Time-specific expression of IL-10 by hepatic macrophages (KC) and stellate cells (HSC) in experimental cholestatic liver injury.
    Miyahara, T
    Wang, SC
    Zuckerman, E
    Lin, M
    Tsukamoto, H
    [J]. HEPATOLOGY, 1997, 26 (04) : 399 - 399
  • [10] Shaping gene expression in activated and resting primary macrophages by IL-10
    Lang, R
    Patel, D
    Morris, JJ
    Rutschman, RL
    Murray, PJ
    [J]. JOURNAL OF IMMUNOLOGY, 2002, 169 (05): : 2253 - 2263
12345