Modulation of N6-Methyladenosine (m6A) by the Fat Mass Obesity-Associated Gene (FTO) Regulates Cardiac Function

被引:0
|
作者
Mathiyalagan, Prabhu
Liang, Yaxuan
Sassi, Yassine
Adamiak, Marta
Ishikawa, Kiyotake
Zhong, Shihong
Kohlbrenner, Erik
Yin, Xiaoke
Chepurko, Elena
Agarwal, Neha
Chen, Jiqiu
Singh, Rajvir
Fish, Kenneth
Mayr, Manuel
Lebeche, Djamel
Hajjar, Roger J.
Sahoo, Susmita
机构
关键词
Ischemic heart disease; Myocardium; Epigenetics; Gene expression; Heart failure;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
17407
引用
收藏
页数:2
相关论文
共 50 条
  • [1] The Potential Role of N6-Methyladenosine (m6A) Demethylase Fat Mass and Obesity-Associated Gene (FTO) in Human Cancers
    Wang, Jin-yan
    Chen, Li-juan
    Qiang, Ping
    [J]. ONCOTARGETS AND THERAPY, 2020, 13 : 12845 - 12856
  • [2] Modulation of m6A in RNA by Fat Mass and Obesity-Associated (FTO) Regulates Cardiac Homeostasis and Contractile Function
    Mathiyalagan, Prabhu
    Adamiak, Marta
    Mayourian, Joshua
    Sassi, Yassine
    Liang Yaxuan
    Agarwal, Neha
    Jha, Divya
    Zhang Shihong
    Kohlbrenner, Erik
    Yin Xiaoke
    Chepurko, Elena
    Chen Jiqiu
    Trivieri, Maria G.
    Singh, Rajvir
    Bouchareb, Rihab
    Fish, Kenneth
    Ishikawa, Kiyotake
    Mayr, Manuel
    Lebeche, Djamel
    Hajjar, Roger J.
    Sahoo, Susmita
    [J]. CIRCULATION, 2018, 138
  • [3] Fat mass and obesity-associated factor (FTO)-mediated N6-methyladenosine regulates spermatogenesis in an age-dependent manner
    Wu, Yifei
    Li, Jincheng
    Li, Chenmeijie
    Lu, Shuai
    Wei, Xiaoyu
    Li, Yang
    Xia, Wenjuan
    Qian, Chunfeng
    Wang, Zihang
    Liu, Mingxi
    Gu, Yayun
    Huang, Boxian
    Tan, Yueqiu
    Hu, Zhibin
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2023, 299 (06)
  • [4] N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO
    Jia, Guifang
    Fu, Ye
    Zhao, Xu
    Dai, Qing
    Zheng, Guanqun
    Yang, Ying
    Yi, Chengqi
    Lindahl, Tomas
    Pan, Tao
    Yang, Yun-Gui
    He, Chuan
    [J]. NATURE CHEMICAL BIOLOGY, 2011, 7 (12) : 885 - 887
  • [5] Cerebroprotective Role of N6-Methyladenosine Demethylase FTO (Fat Mass and Obesity-Associated Protein) After Experimental Stroke
    Chokkalla, Anil K.
    Jeong, Soomin
    Mehta, Suresh L.
    Davis, Charles K.
    Morris-Blanco, Kahlilia C.
    Bathula, Saivenkateshkomal
    Qureshi, Simran S.
    Vemuganti, Raghu
    [J]. STROKE, 2023, 54 (01) : 245 - 254
  • [6] N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO
    Guifang Jia
    Ye Fu
    Xu Zhao
    Qing Dai
    Guanqun Zheng
    Ying Yang
    Chengqi Yi
    Tomas Lindahl
    Tao Pan
    Yun-Gui Yang
    Chuan He
    [J]. Nature Chemical Biology, 2011, 7 : 885 - 887
  • [7] N6-Methyladenosine Demethylase FTO (Fat Mass and Obesity-Associated Protein) as a Novel Mediator of Statin Effects in Human Endothelial Cells
    Mo, Wentao
    Chen, Ziqi
    Zhang, Xiaozhe
    Dai, Gang
    Ma, Dongwei
    Pan, Jiajie
    Zhang, Xinxia
    Wu, Guifu
    Fan, Wendong
    [J]. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2022, 42 (05) : 644 - 658
  • [8] Correction: Corrigendum: N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO
    Guifang Jia
    Ye Fu
    Xu Zhao
    Qing Dai
    Guanqun Zheng
    Ying Yang
    Chengqi Yi
    Tomas Lindahl
    Tao Pan
    Yun-Gui Yang
    Chuan He
    [J]. Nature Chemical Biology, 2012, 8 : 1008 - 1008
  • [9] The N6-methyladenosine (m6A) erasers alkylation repair homologue 5 (ALKBH5) and fat mass and obesity-associated protein (FTO) are prognostic biomarkers in patients with clear cell renal carcinoma
    Strick, Alexander
    von Hagen, Felix
    Gundert, Larissa
    Kluemper, Niklas
    Tolkach, Yuri
    Schmidt, Doris
    Kristiansen, Glen
    Toma, Marieta
    Ritter, Manuel
    Ellinger, Joerg
    [J]. BJU INTERNATIONAL, 2020, 125 (04) : 617 - 624
  • [10] Characteristics of n6-methyladenosine (m6A) regulators and role of FTO/ TNC in scleroderma
    Yu, Yue
    Liang, Chen
    Tang, Qinyu
    Shi, Yuling
    Shen, Liangliang
    [J]. GENE, 2024, 894