THE FARNESOID-X-RECEPTOR AGONIST OBETICHOLIC ACID FURTHER INCREASES BILIARY EXCRETION OF ASYMMETRIC DIMETHYLARGININE DURING HEPATIC ISCHEMIA/REPERFUSION INJURY

被引：0
|
作者：
Di Pasqua, L. G. [1 ]
Berardo, C. [1 ]
Rizzo, V. [2 ]
Adorini, L. [3 ]
Richelmi, P. [1 ]
Vairetti, M. [1 ]
Ferrigno, A. [1 ]
机构：
[1] Univ Pavia, Dept Internal Med & Therapeut, Pavia, Italy
[2] Univ Pavia, Dept Mol Med, IRCCS San Matteo, Pavia, Italy
[3] Intercept Pharmaceut, San Diego, CA USA
来源：
JOURNAL OF HEPATOLOGY | 2016年 / 64卷
关键词：
D O I：
10.1016/S0168-8278(16)00423-2
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
THU-421
引用
收藏
页码：S315 / S315
页数：1
相关论文
共 21 条
  • [1] FURTHER INCREASE IN BILIARY EXCRETION OF ASYMMETRIC DIMETHYLARGININE DURING HEPATIC ISCHEMIA/REPERFUSION INJURY BY OBETICHOLIC ACID, A FARNESOID-X-RECEPTOR AGONIST
    Di Pasqua, L. G.
    Berardo, C.
    Rizzo, V.
    Adorini, L.
    Richelmi, P.
    Vairetti, M.
    Ferrigno, A.
    DIGESTIVE AND LIVER DISEASE, 2016, 48 : E55 - E55
  • [2] The farnesoid X receptor agonist obeticholic acid upregulates biliary excretion of asymmetric dimethylarginine via MATE-1 during hepatic ischemia/reperfusion injury
    Ferrigno, Andrea
    Di Pasqua, Laura Giuseppina
    Berardo, Clarissa
    Siciliano, Veronica
    Rizzo, Vittoria
    Adorini, Luciano
    Richelmi, Plinio
    Vairetti, Mariapia
    PLOS ONE, 2018, 13 (01):
  • [3] Upregulation of MATE-1 transporter by obeticholic acid correlates with increased biliary excretion of asymmetric dimethylarginine during hepatic ischemia/reperfusion injury
    Di Pasqua, L. G.
    Berardo, C.
    Siciliano, V.
    Rizzo, V.
    Adorini, L.
    Richelmi, P.
    Ferrigno, A.
    Vairetti, M.
    JOURNAL OF HEPATOLOGY, 2017, 66 (01) : S613 - S613
  • [4] Increase in transporter MATE-1 expression induced by obeticholic acid correlates with higher biliary excretion of asymmetric dimethylarginine during hepatic ischemia/reperfusion injury
    Di Pasqua, L. G.
    Berardo, C.
    Siciliano, V.
    Viscusi, R.
    Rizzo, V.
    Adorini, L.
    Richelmi, P.
    Ferrigno, A.
    Vairetti, M.
    DIGESTIVE AND LIVER DISEASE, 2017, 49 (01) : E30 - E30
  • [5] Effects of farnesoid-X-receptor SUMOylation mutation on myocardial ischemia/reperfusion injury in mice
    Gao, Yi
    Zhao, Yichao
    Yuan, Ancai
    Xu, Longwei
    Huang, Xian
    Su, Yuanyuan
    Gao, Lingchen
    Ji, Qingqi
    Pu, Jun
    He, Ben
    EXPERIMENTAL CELL RESEARCH, 2018, 371 (02) : 301 - 310
  • [6] Farnesoid-X-Receptor Aggravate Liver Ischemia Reperfusion Injury By Transcriptional Suppress Autophagy
    Zhao, Qiang
    Chen, Maogen
    Fu, Shunjun
    Guo, Zhiyong
    He, Xiaoshun
    TRANSPLANTATION, 2016, 100 : S79 - S80
  • [7] Obeticholic acid reduces biliary and hepatic matrix metalloproteinases activity in rat hepatic ischemia/reperfusion injury
    Ferrigno, Andrea
    Palladini, Giuseppina
    Di Pasqua, Laura Giuseppina
    Berardo, Clarissa
    Richelmi, Plinio
    Cadamuro, Massimiliano
    Fabris, Luca
    Perlini, Stefano
    Adorini, Luciano
    Vairetti, Mariapia
    PLOS ONE, 2020, 15 (09):
  • [8] Bilary excretion of asymmetric (ADMA) and symmetric (SDMA) dimethylarginine during ischemia/reperfusion injury
    Ferrigno, A.
    Rizzo, V.
    Bianchi, A.
    Richelmi, P.
    Vairetti, M.
    DIGESTIVE AND LIVER DISEASE, 2010, 42 : S314 - +
  • [9] Farnesoid X receptor agonist reduces serum asymmetric dimethylarginine levels through hepatic dimethylarginine dimethylaminohydrolase-1 gene regulation
    Hu, Tonghuan
    Chouinard, Michael
    Cox, Amy L.
    Sipes, Philip
    Marcelo, Marialuisa
    Ficorilli, James
    Li, Shuyu
    Gao, Hong
    Ryan, Timothy P.
    Michael, M. Dodson
    Michael, Laura F.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2006, 281 (52) : 39831 - 39838
  • [10] Protective Role of Farnesoid-X Receptor (FXR) Agonist in Intestinal Ischemia Reperfusion Injury.
    Ceulemans, Laurens J.
    Verbeke, Len
    Decuypere, Jean-Paul
    De Hertogh, Gert
    Farre, Ricard
    Lenaerts, Kaatje
    Nevens, Frederik
    Laleman, Wim
    Pirenne, Jacques
    TRANSPLANTATION, 2015, 99 : S49 - S50
123