Development and Characterization of Mouse Models of Infection with Aerosolized Brucella melitensis and Brucella suis

被引：20
|
作者：
Smither, Sophie J. [1 ]
Perkins, Stuart D. [1 ]
Davies, Carwyn [1 ]
Stagg, Anthony J. [1 ]
Nelson, Michelle [1 ]
Atkins, Helen S. [1 ]
机构：
[1] Def Sci & Technol Lab, Salisbury SP4 0JQ, Wilts, England
来源：
CLINICAL AND VACCINE IMMUNOLOGY | 2009年 / 16卷 / 05期
关键词：
CHALLENGE; MICE;
D O I：
10.1128/CVI.00029-09
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
There is a need to identify vaccines that can protect against Brucella, a potential bioterrorism agent. We have developed mouse models of infection with aerosolized Brucella melitensis and Brucella suis and demonstrated their utility for the evaluation of vaccines using the model live B. melitensis vaccine strain Rev.1.
引用
收藏
页码：779 / 783
页数：5
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