HBV Infection and Hepatocellular Carcinoma

被引：37
|
作者：
Iavarone, Massimo [1 ]
Colombo, Massimo [1 ]
机构：
[1] Univ Milan, Fdn IRCCS Ca Granda Maggiore Hosp, Div Gastroenterol 1, AM & A Migliavacca Ctr Liver Dis, I-20122 Milan, Italy
来源：
CLINICS IN LIVER DISEASE | 2013年 / 17卷 / 03期
关键词：
Hepatitis B; Hepatocellular carcinoma; Interferon; Nucleos(t)ide analogues; Surveillance; HEPATITIS-B-VIRUS; PRIMARY LIVER-CANCER; C VIRAL-INFECTION; INTRAHEPATIC RECURRENCE; PROSPECTIVE VALIDATION; INTERFERON TREATMENT; CIRRHOTIC-PATIENTS; RISK-FACTORS; SURVEILLANCE; METAANALYSIS;
D O I：
10.1016/j.cld.2013.05.002
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
The hepatitis B virus (HBV) plays a dominant role in the 749,000 new cases and 692,000 deaths related to hepatocellular carcinoma (HCC) that are estimated to occur each year worldwide. Chronic infection with HBV is responsible for 60% of HCCs in Asia and Africa and at least 20% of the tumors in Europe, Japan, and the United States. This article discusses the pathogenic role of HBV and the risk of HCC. Tumors almost invariably develop in the context of chronic hepatitis or cirrhosis, which makes early diagnosis the only practical approach to improve prognosis. The treatment options are also discussed.
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页码：375 / +
页数：24
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