Inhaled human insulin: An inspiration for patients with diabetes mellitus?

被引:7
|
作者
Davidson, Michael B. [1 ]
Mehta, Adi E. [1 ]
Siraj, Elias S. [1 ]
机构
[1] Cleveland Clin, Dept Endocrinol Diabet & Metab, Cleveland, OH 44195 USA
关键词
D O I
10.3949/ccjm.73.6.569
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Inhaled insulin offers a novel option for controlling blood glucose levels in type 1 and type 2 diabetes, obviating the need for multiple daily injections. The first of several delivery systems, insulin Exubera, was recently approved by the US Food and Drug Administration (FDA). However, questions remain regarding its efficacy, cost-effectiveness, and possible deleterious effects on pulmonary function. This review will discuss the pharmacology, efficacy, important clinical trials, and practical aspects of inhaled insulin, and potential concerns associated with its use.
引用
收藏
页码:569 / 578
页数:10
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