Incorporating Bayesian ideas into health-care evaluation

被引:93
|
作者
Spiegelhalter, DJ [1 ]
机构
[1] MRC, Inst Publ Hlth, Biostat Unit, Cambridge CB2 2SR, England
关键词
Bayes theorem; prior distributions; sceptical prior distribution; data monitoring committee; cost-effectiveness analysis; historical data; decision theory;
D O I
10.1214/088342304000000080
中图分类号
O21 [概率论与数理统计]; C8 [统计学];
学科分类号
020208 ; 070103 ; 0714 ;
摘要
We argue that the Bayesian approach is best seen as providing additional tools for those carrying out health-care evaluations, rather than replacing their traditional methods. A distinction is made between those features that arise from the basic Bayesian philosophy and those that come from the modem ability to make inferences using very complex models. Selected examples of the former include explicit recognition of the wide cast of stakeholders in any evaluation, simple use of Bayes theorem and use of a community of prior distributions. In the context of complex models, we selectively focus on the possible role of simple Monte Carlo methods, alternative structural models for incorporating historical data and making inferences on complex functions of indirectly estimated parameters. These selected issues are illustrated by two worked examples presented in a standardized format. The emphasis throughout is on inference rather than decision-making.
引用
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页码:156 / 174
页数:19
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